SCHEMBL4816936

SCHEMBL4816936

C#CCNc1nc2ccccc2o1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.51
RAB9A P51151 9/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
PKM P14618 3/20 0.51
NPSR1 Q6W5P4 2/20 0.51
GAA P10253 2/20 0.51
ALDH1A1 P00352 1/20 0.51
MAPT P10636 3/20 0.49
PCSK9 Q8NBP7 5/20 0.46
TP53 P04637 2/20 0.46
LMNA P02545 1/20 0.46
ALOX15 P16050 1/20 0.46
CSNK1D P48730 1/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
HSP90AA1 P07900 1/20 0.43
PSMB8 P28062 1/20 0.42
ELANE P08246 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7540148 0.82 NPC1 (0.50) NPC1RAB9ASMN1; SMN2PKMNPSR1
SCHEMBL11451768 0.81 ELANE (0.61) NPC1RAB9ASMN1; SMN2PKMNPSR1
SCHEMBL11047855 0.78 FBP1 (0.49) SMN1; SMN2GAAALDH1A1MAPTLMNA
SCHEMBL10363038 0.78 ELANE (0.71) NPC1RAB9ASMN1; SMN2ALDH1A1ELANE
SCHEMBL18013087 0.78 ELANE (0.63) NPC1RAB9ASMN1; SMN2PKMNPSR1
SCHEMBL11048020 0.77 IL6 (0.41) NPC1RAB9ASMN1; SMN2GAAALDH1A1
SCHEMBL3948639 0.77 PCSK9 (0.54) NPC1RAB9ASMN1; SMN2PKMNPSR1
SCHEMBL5021496 0.77 PCSK9 (0.59) NPC1RAB9ASMN1; SMN2PKMNPSR1
SCHEMBL18013093 0.75 ELANE (0.65) NPC1RAB9ASMN1; SMN2PKMNPSR1
SCHEMBL1990188 0.75 KDM4E (0.53) NPC1RAB9ASMN1; SMN2PKMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0939336-B1 New product and new process for obtaining industrial radiography EASTMAN KODAK CO (US) 2003-11-12 EP claimed
EP-1740579-B1 TRICYCLIC PYRAZOLE KINASE INHIBITORS ABBVIE INC (US) 2015-08-19 EP disclosed
US-7468371-B2 Tricyclic pyrazole kinase inhibitors ABBOTT LABORATORIES INC. (US) 2008-12-23 US disclosed
US-7410745-B2 Photothermographic material and image forming method using same FUJIFILM CORPORATION (JP) 2008-08-12 US disclosed
US-7309564-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-18 US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 US disclosed
EP-1818718-A2 Photothermographic material and method of thermal development of the same Fuji Photo Film Co., Ltd. (JP) 2007-08-15 EP disclosed
EP-1431813-B1 Photothermographic material with high iodide content and image forming method using same FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
EP-1740579-A1 TRICYCLIC PYRAZOLE KINASE INHIBITORS Abbott Laboratories (US) 2007-01-10 EP disclosed
EP-0641459-A1 DYE IMAGE FORMING PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (US) 1995-03-08 EP disclosed
US-5356764-A Color photography EASTMAN KODAK COMPANY (US) 1994-10-18 US disclosed
WO-1994022054-A1 DYE IMAGE FORMING PHOTOGRAPHIC ELEMENTS EASTMAN KODAK COMPANY (US) 1994-09-29 WO disclosed
EP-0617325-A1 Method of processing originating photographic elements containing tabular silver chloride grains bounded by (100) faces EASTMAN KODAK COMPANY (US) 1994-09-28 EP disclosed
EP-0476102-A1 CONTROL OF PRESSURE-FOG WITH GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED SOFT POLYMER LATEX PARTICLES EASTMAN KODAK COMPANY (US) 1992-03-25 EP disclosed
US-5066572-A CONTROL OF PRESSURE-FOG WITH GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED SOFT POLYMER LATEX PARTICLES EASTMAN KODAK COMPANY (US) 1991-11-19 US disclosed
WO-1991014968-A1 CONTROL OF PRESSURE-FOG WITH GELATIN-GRAFTED AND CASE-HARDENED GELATIN-GRAFTED SOFT POLYMER LATEX PARTICLES EASTMAN KODAK COMPANY (US) 1991-10-03 WO disclosed
WO-1991006037-A1 COLOR PHOTOGRAPHIC RECORDING MATERIAL EASTMAN KODAK COMPANY (US) 1991-05-02 WO disclosed
US-4451557-A Photographic speed increasing and latent image stabilizing compounds, silver halide emulsions, and photographic elements EASTMAN KODAK COMPANY (US) 1984-05-29 US disclosed
US-4378426-A Photographic speed increasing and latent image stabilizing compounds, silver halide emulsions, and photographic elements EASTMAN KODAK COMPANY (US) 1983-03-29 US disclosed