SCHEMBL481736

SCHEMBL481736

CC(C)(C)OC(=O)N1CCCC(CN)C1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
BACE1 P56817 2/20 0.50
CTSD P07339 1/20 0.50
GLS O94925 2/20 0.49
HPGD P15428 1/20 0.49
ACKR3 P25106 1/20 0.47
NR1H2 P55055 1/20 0.47
FEN1 P39748 2/20 0.45
KDM1A O60341 1/20 0.45
SCN9A Q15858 1/20 0.45
EPHX1 P07099 1/20 0.43
ALOX5AP P20292 1/20 0.43
CYP2C9 P11712 1/20 0.43
CHEK2 O96017 1/20 0.43
USP30 Q70CQ3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1192567 1.00 MEN1 (0.54) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL640559 1.00 MEN1 (0.54) MEN1ALDH1A1MAPTKMT2ABACE1
Hydrochloric Acid SCHEMBL31587983 0.98 MEN1 (0.53) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL2069709 0.95 HPGD (0.51) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL28110777 0.94 HPGD (0.51) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL321665 0.91 NR1H2 (0.49) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL346504 0.91 NR1H2 (0.49) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL6197 0.91 NR1H2 (0.49) MEN1ALDH1A1MAPTKMT2AHPGD
Hydrochloric Acid SCHEMBL28558235 0.89 NR1H2 (0.48) MEN1ALDH1A1MAPTKMT2AHPGD
Hydrochloric Acid SCHEMBL1290905 0.89 NR1H2 (0.48) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 664 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS WILMINGTON TRUST, NATIONAL ASSOCIATION 2026-04-02 US disclosed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
EP-4620949-A1 ACKR3 MODULATORS FOR CARDIOVASCULAR OR ANTIPLATELET THERAPY Eberhard Karls Universität Tübingen (Medizinische Fakultät) (DE) 2025-09-24 EP disclosed
EP-4616913-A2 GCN2 INHIBITORS AND USES THEREOF Merck Patent GmbH (DE) 2025-09-17 EP disclosed
EP-3261631-B1 INHIBITION OF OLIG2 ACTIVITY CURTANA PHARMACEUTICALS INC (US) 2025-09-10 EP disclosed
EP-3746075-B1 GCN2 INHIBITORS AND USES THEREOF MERCK PATENT GMBH (DE) 2025-09-03 EP disclosed
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT ABBVIE INC (US) 2025-05-22 US disclosed
EP-4524133-A2 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS Biocryst Pharmaceuticals, Inc. (US) 2025-03-19 EP disclosed
US-20250019364-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES ABBVIE INC. (US) 2025-01-16 US disclosed
EP-4474383-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2024-12-11 EP disclosed
EP-1317442-A1 QUINOLINONE DERIVATIVES AS TYROSINE KINASE INHIBITORS CHIRON CORPORATION (US) 2003-06-11 EP disclosed
WO-2003015785-A1 2H-PHTHALAZIN-1-ONES AND METHODS FOR USE THEREOF ICOS CORPORATION (US) 2003-02-27 WO disclosed
US-20030028018-A1 Quinolinone derivatives CHIRON COPORATION 2003-02-06 US disclosed
US-20020193405-A1 Thiazolyl urea compounds and methods of uses AMGEN INC. 2002-12-19 US disclosed
EP-1243589-A1 Heteroaryl-substituted pyrrole derivates, their preparation and their therapeutic uses Sankyo Company Limited (JP) 2002-09-25 EP disclosed
US-20020107392-A1 Quinolinone derivatives NOVARTIS AG (CH) 2002-08-08 US disclosed
EP-1213281-A1 NOVEL AMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-06-12 EP disclosed
WO-2002022598-A1 QUINOLINONE DERIVATIVES AS TYROSINE KINASE INHIBITORS CHIRON CORPORATION (US) 2002-03-21 WO disclosed
CN-1295069-A Heteraryl-substituted porrole derivatives, their prep. and therapeutic use SANKYO CO (JP) 2001-05-16 CN disclosed
EP-1070711-A2 Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses Sankyo Company Limited (JP) 2001-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020193405-A1 Thiazolyl urea compounds and methods of uses SLC14A1, UMPS, BAX MEN1 1181/4885ALDH1A1 810/4885MAPT 1437/4885
US-20030028018-A1 Quinolinone derivatives SLCO1B1, SLCO1B3, SLCO1A2 MEN1 992/4885ALDH1A1 232/4885MAPT 2067/4885
US-20260092045-A1 SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS TFPI, F3, BTK MEN1 1627/4885ALDH1A1 3179/4885MAPT 263/4885
US-20020107392-A1 Quinolinone derivatives SLCO1B1, SLCO1B3, SLCO1A2 MEN1 992/4885ALDH1A1 232/4885MAPT 2067/4885
US-20250019364-A1 APOPTOSIS INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES BCL2, BAX, BCL3 MEN1 3634/4885ALDH1A1 4238/4885MAPT 3890/4885
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT BCL2, BAX, BCL2L1 MEN1 4081/4885ALDH1A1 4457/4885MAPT 3062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.