SCHEMBL640559

SCHEMBL640559

CC(C)(C)OC(=O)N1CCC[C@@H](CN)C1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
KMT2A Q03164 1/20 0.54
BACE1 P56817 2/20 0.50
CTSD P07339 1/20 0.50
GLS O94925 2/20 0.49
HPGD P15428 1/20 0.49
ACKR3 P25106 1/20 0.47
NR1H2 P55055 1/20 0.47
FEN1 P39748 2/20 0.45
KDM1A O60341 1/20 0.45
SCN9A Q15858 1/20 0.45
EPHX1 P07099 1/20 0.43
ALOX5AP P20292 1/20 0.43
CYP2C9 P11712 1/20 0.43
CHEK2 O96017 1/20 0.43
USP30 Q70CQ3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1192567 1.00 MEN1 (0.54) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL481736 1.00 MEN1 (0.54) MEN1ALDH1A1MAPTKMT2ABACE1
Hydrochloric Acid SCHEMBL31587983 0.98 MEN1 (0.53) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL2069709 0.95 HPGD (0.51) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL28110777 0.94 HPGD (0.51) MEN1ALDH1A1MAPTKMT2ABACE1
SCHEMBL321665 0.91 NR1H2 (0.49) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL346504 0.91 NR1H2 (0.49) MEN1ALDH1A1MAPTKMT2AHPGD
SCHEMBL6197 0.91 NR1H2 (0.49) MEN1ALDH1A1MAPTKMT2AHPGD
Hydrochloric Acid SCHEMBL28558235 0.89 NR1H2 (0.48) MEN1ALDH1A1MAPTKMT2AHPGD
Hydrochloric Acid SCHEMBL1290905 0.89 NR1H2 (0.48) MEN1ALDH1A1MAPTKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 200 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2670722-B1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO-{N-[(3-T-BUTOXYCARBONYL-AMINOMETHYL)]-PIPERIDIN-1-YL}-PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION COUNCIL SCIENT IND RES (IN) 2016-10-12 EP claimed
US-20130338193-A1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO--PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2013-12-19 US claimed
EP-2670722-A1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO-{N-[(3-T-BUTOXYCARBONYL-AMINOMETHYL)]-PIPERIDIN-1-YL}-PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION Council of Scientific & Industrial Research (IN) 2013-12-11 EP claimed
WO-2012104866-A1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO-{N-[(3-T-BUTOXYCARBONYL- AMINOMETHYL)]-PIPERIDIN-1-YL}-PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2012-08-09 WO claimed
WO-2026085629-A1 SUBSTITUTED HETEROCYCLIC COMPOUNDS, COMPOSITIONS COMPRISING THEM AND USES THEREOF Université de Montréal (CA) 2026-04-30 WO disclosed
EP-4680601-A1 PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES Sanofi (FR) 2026-01-21 EP disclosed
US-20250270191-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. 2025-08-28 US disclosed
US-20250206745-A1 PYRROLOPYRIDAZINE DERIVATIVES AND RELATED USES NODTHERA LTD (GB) 2025-06-26 US disclosed
US-12338230-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders ACHILLION PHARMACEUTICALS, INC. (US) 2025-06-24 US disclosed
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-04-24 US disclosed
EP-4536649-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS Treeline Biosciences, Inc. (US) 2025-04-16 EP disclosed
WO-2025064718-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 WO disclosed
US-6919356-B2 N-substituted heterocyclic amines as modulators of chemokine receptor activity BRISTOL MYERS SQUIBB COMPANY (US) 2005-07-19 US disclosed
US-6809108-B1 SELECTIVE MUSCARINIC M3 RECEPTOR ANTAGONTS; REDUCED SIDE EFFECTS BANYU PHARMACEUTICAL CO., LTD. (JP) 2004-10-26 US disclosed
US-20040204369-A1 Novel amide derivatives MSD K.K. (JP) 2004-10-14 US disclosed
WO-2004028530-A1 N-SUBSTITUTED HETEROCYCLIC AMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL-MYERS SQUIBB COMPANY (US) 2004-04-08 WO disclosed
US-20040067935-A1 N-substituted heterocyclic amines as modulators of chemokine receptor activity BRISTOL-MYERS SQUIBB COMPANY 2004-04-08 US disclosed
EP-1213281-B1 NOVEL AMIDE DERIVATIVES BANYU PHARMA CO LTD (JP) 2004-02-18 EP disclosed
EP-1213281-A1 NOVEL AMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2002-06-12 EP disclosed
CN-1076690-A SULFONAMIDOCARBOXAMIDES HOFFMANN LA ROCHE (CH) 1993-09-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040204369-A1 Novel amide derivatives CHRM3, CHRM1, CHRM2 MEN1 490/4885ALDH1A1 1744/4885MAPT 4544/4885
US-12338230-B2 Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders CFD, TFPI, CFH MEN1 2099/4885ALDH1A1 2717/4885MAPT 4523/4885
US-20250270191-A1 QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS BCL6, BCL6B, BCOR MEN1 1552/4885ALDH1A1 291/4885MAPT 4449/4885
US-20250206745-A1 PYRROLOPYRIDAZINE DERIVATIVES AND RELATED USES IL1B, NLRP3, NLRP1 MEN1 3038/4885ALDH1A1 226/4885MAPT 3788/4885
US-20250129021-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS MEN1 798/4885ALDH1A1 2630/4885MAPT 2071/4885
US-20130338193-A1 CHIRAL 1-(4-METHYLPHENYLMETHYL)-5-OXO--PYRROLIDINE-2-CARBOXAMIDES AS INHIBITORS OF COLLAGEN INDUCED PLATELET ACTIVATION AND ADHESION PLOD1, PLOD3, PLOD2 MEN1 4712/4885ALDH1A1 1117/4885MAPT 4222/4885
US-20040067935-A1 N-substituted heterocyclic amines as modulators of chemokine receptor activity CCL11, ACKR3, CCR7 MEN1 3653/4885ALDH1A1 536/4885MAPT 4733/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.