Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL75027 | 0.79 | CYP1A2 (0.34) | CYP1A2SIGMAR1HPGDCHRM5ADRA2C | |
| SCHEMBL5671309 | 0.78 | SIGMAR1 (0.38) | CYP1A2SIGMAR1HPGDMETAP1EPHX1 | |
| SCHEMBL14209302 | 0.76 | CYP1A2 (0.31) | CYP1A2PDK1PDK2PDK3PDK4 | |
| SCHEMBL5670650 | 0.76 | SIGMAR1 (0.34) | CYP1A2SIGMAR1HPGDMETAP1KDM4E | |
| SCHEMBL24535449 | 0.75 | CYP1A2 (0.44) | CYP1A2SIGMAR1HPGDCHRM5ADRA2C | |
| SCHEMBL10463427 | 0.75 | CYP1A2 (0.44) | CYP1A2SIGMAR1HPGDCHRM5ADRA2C | |
| SCHEMBL13744086 | 0.72 | LIPA (0.30) | — | |
| SCHEMBL18785769 | 0.72 | HPGD (0.35) | CYP1A2SIGMAR1HPGDCHRM5ADRA2C | |
| SCHEMBL27436730 | 0.71 | CYP1A2 (0.46) | CYP1A2SIGMAR1HPGDCHRM5ADRA2C | |
| SCHEMBL291415 | 0.71 | CYP1A2 (0.46) | CYP1A2SIGMAR1HPGDMETAP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385091-B2 | Process for producing fluorine-containing diol and its derivatives | CENTRAL GLASS CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7385091-B2 | Process for producing fluorine-containing diol and its derivatives | CENTRAL GLASS CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-7385091-B2 | Process for producing fluorine-containing diol and its derivatives | CENTRAL GLASS CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20070032684-A1 | Process for producing fluorine-containing diol and its derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032684-A1 | Process for producing fluorine-containing diol and its derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032684-A1 | Process for producing fluorine-containing diol and its derivatives | CENTRAL GLASS COMPANY, LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032684-A1 | Process for producing fluorine-containing diol and its derivatives | HDHD5, ADH1A, AFF1 | CYP1A2 103/4885SIGMAR1 3210/4885HPGD 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.