Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.73 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.73 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.58 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | DRD3 | P35462 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | STAT6 | P42226 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12447796 | 0.86 | TMEM97 (0.75) | TMEM97SIGMAR1PRMT5WDR77LMNA | |
| SCHEMBL12391543 | 0.85 | TMEM97 (1.00) | TMEM97SIGMAR1PRMT5WDR77LMNA | |
| SCHEMBL12886873 | 0.82 | TMEM97 (0.70) | TMEM97SIGMAR1PRMT5WDR77LMNA | |
| SCHEMBL17816986 | 0.81 | MGLL (0.65) | POLBMEN1KMT2A | |
| SCHEMBL11619911 | 0.79 | MCHR1 (0.69) | TMEM97SIGMAR1LMNAKCNH2ADRA2A | |
| SCHEMBL31379986 | 0.79 | KMT2A (0.56) | TMEM97SIGMAR1LMNAKCNH2ADRA2A | |
| SCHEMBL10379993 | 0.78 | LMNA (0.68) | TMEM97SIGMAR1LMNAKCNH2CYP2D6 | |
| SCHEMBL1209964 | 0.78 | LMNA (0.72) | TMEM97SIGMAR1LMNAKCNH2TSHR | |
| SCHEMBL2442620 | 0.76 | LMNA (0.58) | TMEM97SIGMAR1LMNAKCNH2TSHR | |
| SCHEMBL22501758 | 0.76 | ACHE (0.56) | LMNAALDH1A1ACHECYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080226550-A1 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| US-7321027-B2 | Small technetium-99m and rhenium labeled agents and methods for imaging tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2008-01-22 | — | — | US | disclosed |
| EP-1276718-B1 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | HARVARD COLLEGE (US) | 2007-04-18 | — | — | EP | disclosed |
| US-20040097735-A1 | Small technetium-99m and rhenium labeled agents and methods for imaging tumors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080226550-A1 | SMALL TECHNETIUM-99M AND RHENIUM LABELED AGENTS AND METHODS FOR IMAGING TUMORS | VHL, MEN1, NRAS | TMEM97 3391/4885SIGMAR1 3722/4885PRMT5 22/4885 |
| US-20040097735-A1 | Small technetium-99m and rhenium labeled agents and methods for imaging tumors | VHL, MEN1, NRAS | TMEM97 3391/4885SIGMAR1 3722/4885PRMT5 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.