Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 12/20 | 0.43 |
| ▸ | MMP3 | P08254 | 9/20 | 0.43 |
| ▸ | MMP9 | P14780 | 8/20 | 0.43 |
| ▸ | MMP13 | P45452 | 8/20 | 0.43 |
| ▸ | MMP1 | P03956 | 11/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4822556 | 1.00 | PLA2G7 (0.43) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL4818302 | 1.00 | PLA2G7 (0.43) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL14156368 | 0.80 | PLA2G7 (0.44) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL6949966 | 0.79 | PLA2G7 (0.44) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL7028144 | 0.78 | MMP2 (0.44) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL7608470 | 0.76 | MMP2 (0.40) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL4756856 | 0.72 | KMT2A (0.56) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL6945464 | 0.71 | PLA2G7 (0.49) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL422413 | 0.71 | PLA2G7 (0.49) | PLA2G7MMP2MMP3MMP9MMP13 | |
| SCHEMBL6547554 | 0.70 | POLB (0.39) | LCKPPARDZDHHC20ZDHHC2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | claimed |
| EP-1324975-B1 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL MYERS SQUIBB CO (US) | 2005-11-16 | — | — | EP | claimed |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-15 | — | — | US | claimed |
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-7388098-B2 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| EP-1324975-B1 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL MYERS SQUIBB CO (US) | 2005-11-16 | — | — | EP | disclosed |
| EP-1324975-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | Bristol-Myers Squibb Company (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-0859784-B1 | THIO-SUBSTITUTED PEPTIDES AS INHIBITORS FOR METALLOPROTEINASES AND TNF LIBERATION | DARWIN DISCOVERY LTD (GB) | 2002-12-18 | — | — | EP | disclosed |
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-15 | — | — | US | disclosed |
| WO-2002028809-A2 | DYNAMIC RESOLUTION OF ISOMERS AND RESOLVED ISOMERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |
| US-5981490-A | ADMINISTERING A PEPTIDYL COMPOUND FOR TREATMENT IN A HUMAN OR ANIMAL OF A CONDITION ASSOCIATED WITH MATRIX METALIOPROTEINASES OR THAT IS MEDIATED BY TUMOR NECROSIS FACTOR ALPHA OR L-SELECTIN SHEDDASE | DARWIN DISCOVERY, LTD. (GB) | 1999-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111512-A1 | Dynamic resolution of isomers and resolved isomers | DHCR24, LPAR1, SLC7A1 | PLA2G7 3331/4885MMP2 2290/4885MMP3 1282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.