Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 16/20 | 0.40 |
| ▸ | MMP9 | P14780 | 14/20 | 0.40 |
| ▸ | MMP3 | P08254 | 8/20 | 0.40 |
| ▸ | MMP13 | P45452 | 7/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 8/20 | 0.38 |
| ▸ | MMP7 | P09237 | 2/20 | 0.38 |
| ▸ | MMP14 | P50281 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 5/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824816 | 0.82 | PLA2G7 (0.46) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL4820309 | 0.82 | PLA2G7 (0.46) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL4820321 | 0.82 | PLA2G7 (0.46) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL4822556 | 0.76 | PLA2G7 (0.43) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL6546709 | 0.76 | MMP2 (0.36) | MMP2MMP9KMT2A | |
| SCHEMBL4818302 | 0.76 | PLA2G7 (0.43) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL6546698 | 0.76 | MMP2 (0.36) | MMP2MMP9KMT2A | |
| SCHEMBL6947897 | 0.76 | CPB2 (0.48) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL7028144 | 0.74 | MMP2 (0.44) | MMP2MMP9MMP3MMP13PLA2G7 | |
| SCHEMBL7604548 | 0.71 | MMP3 (0.63) | MMP2MMP9MMP3MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0859784-B1 | THIO-SUBSTITUTED PEPTIDES AS INHIBITORS FOR METALLOPROTEINASES AND TNF LIBERATION | DARWIN DISCOVERY LTD (GB) | 2002-12-18 | — | — | EP | disclosed |