Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.34 |
| ▸ | GLP1R | P43220 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824084 | 0.80 | KMT2A (0.38) | L3MBTL1KCNQ3KCNQ2SMN1; SMN2NPC1 | |
| SCHEMBL4824592 | 0.80 | L3MBTL1 (0.42) | L3MBTL1KCNQ3KCNQ2SMN1; SMN2NPC1 | |
| SCHEMBL4823413 | 0.78 | KMT2A (0.36) | L3MBTL1KCNQ3KCNQ2SMN1; SMN2NPC1 | |
| SCHEMBL4818544 | 0.78 | KMT2A (0.41) | L3MBTL1KCNQ3KCNQ2SMN1; SMN2NPC1 | |
| SCHEMBL4670838 | 0.78 | KCNQ3 (0.37) | L3MBTL1KCNQ3KCNQ2SMN1; SMN2NPC1 | |
| SCHEMBL4818188 | 0.71 | KCNQ3 (0.43) | L3MBTL1KCNQ3KCNQ2SMN1; SMN2RAB9A | |
| SCHEMBL4820597 | 0.66 | OPRM1 (0.32) | LMNA | |
| SCHEMBL4824601 | 0.61 | MEN1 (0.44) | L3MBTL1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL27252118 | 0.60 | KMT2A (0.39) | L3MBTL1RAB9AKMT2AMEN1FFAR2 | |
| SCHEMBL4824088 | 0.60 | MEN1 (0.39) | L3MBTL1SMN1; SMN2RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146621-A1 | Polysubstituted 1,1-pyridylaminocyclopropanamine compounds | LES LABORATORIES SERVIER (FR) | 2008-06-19 | — | — | US | disclosed |
| US-7388022-B2 | Polysubstituted 1,1-pyridylaminocyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2008-06-17 | — | — | US | disclosed |
| US-20070027192-A1 | Polysubstituted 1,1-pyridylamioncyclopropanamine compounds | LES LABORATOIRES SERVIER (FR) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146621-A1 | Polysubstituted 1,1-pyridylaminocyclopropanamine compounds | CHRNA1, CHRM1, CHRNA9 | L3MBTL1 3231/4885KCNQ3 1244/4885KCNQ2 1214/4885 |
| US-20070027192-A1 | Polysubstituted 1,1-pyridylamioncyclopropanamine compounds | CHRM1, CHRM2, CHRM3 | L3MBTL1 2522/4885KCNQ3 1192/4885KCNQ2 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.