Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 2/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OXTR | P30559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4670355 | 0.81 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2MEN1L3MBTL1LMNA | |
| SCHEMBL4818540 | 0.78 | L3MBTL1 (0.39) | KCNQ3KCNQ2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL4818544 | 0.78 | KMT2A (0.41) | KCNQ3KCNQ2KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7667371 | 0.65 | MEN1 (0.49) | KMT2ASMN1; SMN2MEN1L3MBTL1LMNA | |
| SCHEMBL27699361 | 0.65 | CTSK (0.51) | KMT2AMEN1 | |
| SCHEMBL7660392 | 0.63 | ALDH1A1 (0.44) | KMT2ASMN1; SMN2MEN1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL4825587 | 0.62 | ALDH1A1 (0.43) | KMT2ASMN1; SMN2MEN1L3MBTL1LMNA | |
| SCHEMBL4672795 | 0.62 | MEN1 (0.34) | KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL7664945 | 0.62 | ROCK2 (0.44) | KMT2AMEN1L3MBTL1LMNAFFAR2 | |
| SCHEMBL4824601 | 0.62 | MEN1 (0.44) | KMT2ASMN1; SMN2MEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757586-B1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | SERVIER LAB (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1757586-A1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | Les Laboratoires Servier (FR) | 2007-02-28 | — | — | EP | disclosed |