SCHEMBL4819951

SCHEMBL4819951

CCC1CCC(C(=O)O)CC1.O=C1C=CC(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 1/20 0.43
PLAT P00750 1/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
CYP2C9 P11712 1/20 0.38
KMT2A Q03164 1/20 0.38
GSK3A P49840 1/20 0.37
GSK3B P49841 1/20 0.37
CCR6 P51684 1/20 0.37
ANPEP P15144 1/20 0.36
ENPEP Q07075 1/20 0.36
ADORA1 P30542 1/20 0.35
S1PR5 Q9H228 1/20 0.35
OPRM1 P35372 1/20 0.34
ENPP2 Q13822 2/20 0.34
GABRP O00591 1/20 0.34
GABRD O14764 1/20 0.34
GABRA1 P14867 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL879831 0.82 LMNA (0.60) PLGPLATLMNAALDH1A1MEN1
Cyclopropane Carboxylic Acid SCHEMBL11636034 0.82 LMNA (0.60) PLGPLATLMNAALDH1A1MEN1
SCHEMBL14643284 0.82 LMNA (0.60) PLGPLATLMNAALDH1A1MEN1
SCHEMBL178465 0.82 LMNA (0.60) PLGPLATLMNAALDH1A1MEN1
SCHEMBL316039 0.81 GSK3A (0.41) PLGPLATLMNAALDH1A1MEN1
Hydrochloric Acid SCHEMBL11310028 0.80 PLG (0.58) PLGPLATLMNAALDH1A1MEN1
Hydrochloric Acid SCHEMBL8903649 0.80 PLG (0.58) PLGPLATLMNAALDH1A1MEN1
SCHEMBL20561062 0.77 GSK3A (0.44) LMNAALDH1A1GSK3AGSK3BCCR6
SCHEMBL2820876 0.76 PLG (0.54) PLGPLATLMNAALDH1A1MEN1
SCHEMBL2820881 0.76 PLG (0.54) PLGPLATLMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004508-A Preparation method of thermostable alkaline phosphatase antibody conjugate 济南国科医工科技发展有限公司 2021-06-22 CN disclosed
US-7374875-B2 Peptides having affinity for the gp120 viral protein and use thereof COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2008-05-20 US disclosed
US-20060121538-A1 Peptides having affinity for the gp120 viral protein and use thereof COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2006-06-08 US disclosed
US-5109124-A NUCLEIC ACID PROBE LINKED TO A LABEL HAVING A TERMINAL CYSTEINE BIOGEN, INC. (US) 1992-04-28 US disclosed
EP-0440647-A1 LABELED NUCLEIC ACID PROBE BIOGEN, INC. (US) 1991-08-14 EP disclosed
WO-1989012110-A1 LABELED NUCLEIC ACID PROBE BIOGEN, INC. (US) 1989-12-14 WO disclosed