Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010933 | 0.82 | GSK3A (0.61) | GSK3AGSK3BCCR6 | |
| SCHEMBL20561062 | 0.81 | GSK3A (0.44) | GSK3AGSK3BCCR6GABRPGABRD | |
| SCHEMBL4819951 | 0.81 | PLG (0.43) | GSK3AGSK3BCCR6GABRPGABRD | |
| SCHEMBL8096130 | 0.80 | ALDH1A1 (0.36) | GSK3AGSK3BCCR6GABRPGABRD | |
| SCHEMBL265529 | 0.79 | LMNA (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL135662 | 0.79 | LMNA (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL135660 | 0.79 | LMNA (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Bicarbonate SCHEMBL9841170 | 0.79 | GSK3A (0.42) | GSK3AGSK3BCCR6RAB9ALMNA | |
| SCHEMBL6908741 | 0.77 | LMNA (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6914968 | 0.77 | LMNA (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 739 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675480-B1 | METHODS OF PREPARATION OF CONJUGATES | IMMUNOGEN INC (US) | 2018-12-26 | — | — | EP | claimed |
| US-9046528-B2 | Cross-reactive determinants and methods for their identification | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-06-02 | — | — | US | claimed |
| EP-2227243-A2 | A PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY-RELATED DISEASE COMPRISING INSULINOTROPIC PEPTIDE CONJUGATE | Hanmi Pharmaceutical Co., Ltd. (KR) | 2010-09-15 | — | — | EP | claimed |
| WO-2009069983-A2 | A PHARMACEUTICAL COMPOSITION FOR TREATING OBESITY-RELATED DISEASE COMPRISING INSULINOTROPIC PEPTIDE CONJUGATE | HANMI PHARMACEUTICAL CO., LTD. (KR) | 2009-06-04 | — | — | WO | claimed |
| EP-0787015-B1 | SYNTHESIS OF TYPHOID FEVER VACCINE FROM A PLANT OR FRUIT POLYSACCHARIDE | US GOV HEALTH & HUMAN SERV (US) | 2002-02-27 | — | — | EP | claimed |
| WO-2024121380-A1 | VACCINAL COMPOSITION AND ADJUVANT | PIERRE FABRE MEDICAMENT (FR) | 2024-06-13 | — | — | WO | disclosed |
| US-11998544-B2 | Methods of using splicing modulators | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-06-04 | — | — | US | disclosed |
| CN-112367996-B | Methods of using splice modulators | 卫材R&D管理有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-11965005-B2 | Multi-epitope vaccine for the treatment of Alzheimer's disease | OTHAIR PROTHENA LIMITED (IE) | 2024-04-23 | — | — | US | disclosed |
| US-11952406-B2 | Multi-epitope vaccine for the treatment of Alzheimer's disease | OTHAIR PROTHENA LIMITED (IE) | 2024-04-09 | — | — | US | disclosed |
| US-11945807-B2 | Splicing modulator antibody-drug conjugates and methods of use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-04-02 | — | — | US | disclosed |
| US-11945849-B2 | Multi-epitope vaccine for the treatment of Alzheimer's disease | OTHAIR PROTHENA LIMITED (IE) | 2024-04-02 | — | — | US | disclosed |
| EP-0257754-A2 | Synthetic peptides of human Papilloma virus | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0251575-A1 | Hepatitis delta diagnostics and vaccines, their preparation and use | CHIRON CORPORATION (US) | 1988-01-07 | — | — | EP | disclosed |
| EP-0208672-A1 | Vaccines and diagnostics derived from bovine diarrhea virus | REGION WALLONNE représentée par le Ministre des Technologies pour la Région wallonne dans ses attributions (BE) | 1987-01-14 | — | — | EP | disclosed |
| US-4622223-A | Broad spectrum vaccine against gonorrhea | THE BOARD OF TRUSTEES FOR THE LELAND STANFORD UNIVERSITY (US) | 1986-11-11 | — | — | US | disclosed |
| EP-0199480-A2 | Hepatitis A virus vaccines | CHIRON CORPORATION (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4584195-A | POLYPEPTIDES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0170496-A2 | Vaccine against urinary tract infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1986-02-05 | — | — | EP | disclosed |
| EP-0166548-A2 | Broad spectrum vaccine against gonorrhea | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 1986-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11945807-B2 | Splicing modulator antibody-drug conjugates and methods of use | RBM17, RBM22, SF3B1 | GSK3A 2321/4885GSK3B 2307/4885CCR6 3479/4885 |
| US-11998544-B2 | Methods of using splicing modulators | SF3B1, RBM17, SF3B5 | GSK3A 3496/4885GSK3B 3548/4885CCR6 3576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.