SCHEMBL4819967

SCHEMBL4819967

CC(C)N(C(C)C)P(CCC#N)OCl

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14338420 0.74 ALDH1A1 (0.31)
SCHEMBL735862 0.74
SCHEMBL1064223 0.74 TSHR (0.33) TSHR
SCHEMBL634591 0.73 TSHR (0.36) TSHR
SCHEMBL8328893 0.73 TSHR (0.36) TSHR
SCHEMBL15617982 0.72 TSHR (0.38) TSHR
SCHEMBL735861 0.72
SCHEMBL14286693 0.72 TSHR (0.38) TSHR
SCHEMBL15268078 0.71
SCHEMBL2554910 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001092285-A1 NOVEL OLIGONUCLEOTIDE COMPOUNDS HAVING PYRROLIZINE DERIVATIVES, PROCESSES FRO PREPARING THEM, COMPOSITIONS CONTAINING THEM AND USES THEREOF IN TREATMENT, DIAGNOSIS AND ANALYSIS OF GENE-RELATED DISEASES GENECHEM INC. (KR) 2001-12-06 WO claimed
US-20240132940-A1 REPORTER AND USES THEREOF SFC CO., LTD. (KR) 2024-04-25 US disclosed
US-7335500-B2 Production of fucosylated carbohydrates by enzymatic fucosylation synthesis of sugar nucleotides; and in situ regeneration of GDP-fucose THE SCRIPPS RESEARCH INSTITUTE (US) 2008-02-26 US disclosed
US-6319695-B1 FORMING A GLYCOSIDE BOND BY ETHERIFICATION AND CIRCULATION THE SCRIPPS RESEARCH INSITUTE 2001-11-20 US disclosed
EP-0642526-B1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE SCRIPPS RESEARCH INST (US) 1998-12-23 EP disclosed
EP-0642526-A4 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE. SCRIPPS RESEARCH INST (US) 1996-04-10 EP disclosed
EP-0642526-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1995-03-15 EP disclosed
WO-1993008205-A1 PRODUCTION OF FUCOSYLATED CARBOHYDRATES BY ENZYMATIC FUCOSYLATION SYNTHESIS OF SUGAR NUCLEOTIDES; AND IN SITU REGENERATION OF GDP-FUCOSE THE SCRIPPS RESEARCH INSTITUTE (US) 1993-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240132940-A1 REPORTER AND USES THEREOF LUC7L2, NSUN3, NUDT21 TSHR 3483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.