SCHEMBL4820095

SCHEMBL4820095

CCCc1cccc(C#N)c1C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.45
CTSS P25774 5/20 0.45
EPHX2 P34913 1/20 0.37
DRD3 P35462 3/20 0.35
DRD2 P14416 2/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
CASP1 P29466 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2042809 0.92 CTSK (0.40) CTSKCTSSDRD3DRD2CYP2D6
SCHEMBL10732209 0.90 CTSK (0.39) CTSKCTSS
SCHEMBL10730136 0.89 CTSK (0.39) CTSKCTSS
SCHEMBL16593855 0.84 EPHX2 (0.44) CTSKCTSSEPHX2DRD3DRD2
SCHEMBL28252845 0.81 KDM4E (0.41) CTSKCTSSDRD3DRD2TSHR
SCHEMBL27810248 0.79 CTSK (0.36) CTSKCTSS
SCHEMBL29144848 0.78 EPHX2 (0.40) CTSKCTSSEPHX2DRD3DRD2
SCHEMBL9493041 0.78 DRD2 (0.36) DRD3DRD2KDM4EALDH1A1NPSR1
SCHEMBL16950823 0.77 HTR2A (0.32) CTSKCTSS
SCHEMBL29255720 0.77 EPHX2 (0.42) CTSKCTSSEPHX2DRD3DRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107842706-A A kind of break-in method of coefficient of friction between reduction metallic rubbing pairs 齐鲁工业大学 2018-03-27 CN claimed
CN-101811984-A Production method of propylcyclohexyl benzonitrile JIANGSU KANGXIANG GROUP COMPANY 2010-08-25 CN claimed
CN-107842706-A A kind of break-in method of coefficient of friction between reduction metallic rubbing pairs 齐鲁工业大学 2018-03-27 CN disclosed
WO-2013055317-A1 LIQUID CRYSTALS WITH SWITCHABLE WETTABILITY FOR CELL SORTING EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2013-04-18 WO disclosed
CN-101811984-A Production method of propylcyclohexyl benzonitrile JIANGSU KANGXIANG GROUP COMPANY 2010-08-25 CN disclosed
CN-101811984-A Production method of propylcyclohexyl benzonitrile JIANGSU KANGXIANG GROUP COMPANY 2010-08-25 CN disclosed
CN-101811984-A Production method of propylcyclohexyl benzonitrile JIANGSU KANGXIANG GROUP COMPANY 2010-08-25 CN disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
US-7115307-B2 Nematic liquid crystal mixtures for bistable display device NEMOPTIC (FR) 2006-10-03 US disclosed
US-4702561-A AMINOANTHRAQUINONE BISANIL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-10-27 US disclosed