Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168402 | 0.88 | GABRA1 (0.37) | DRD2DRD3GABRA1GABRB2ALDH1A1 | |
| SCHEMBL14692733 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL9327041 | 0.82 | KMT2A (0.33) | GABRA1ALDH1A1KDM4EKMT2AGABRG2 | |
| SCHEMBL436471 | 0.81 | KMT2A (0.34) | DRD2DRD3GABRA1GABRB2ALDH1A1 | |
| SCHEMBL28252845 | 0.79 | KDM4E (0.41) | DRD2DRD3ALDH1A1KDM4EMAOA | |
| SCHEMBL491175 | 0.79 | GABRA1 (0.46) | DRD2GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL27919603 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL4820095 | 0.78 | CTSK (0.45) | DRD2DRD3ALDH1A1KDM4ENPSR1 | |
| SCHEMBL28887861 | 0.78 | DRD2 (0.33) | DRD2DRD3ALDH1A1KDM4EMAOA | |
| SCHEMBL27631593 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232052-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION | Chisso Corporation (JP) | 1993-03-24 | — | — | EP | disclosed |
| EP-0280902-B1 | CYCLOHEXANE DERIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | CHISSO CORPORATION (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4820443-A | LOW VISCOSITY, LOW VOLTAGE | CHISSO CORPORATION (JP) | 1989-04-11 | — | — | US | disclosed |
| US-4776975-A | LOW THRESHOLD VOLTAGE AND TEMPERATURE DEPENDENCY | CHISSO CORPORATION (JP) | 1988-10-11 | — | — | US | disclosed |