Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187861 | 0.84 | TSHR (0.52) | TSHRSMN1; SMN2ALDH1A1TDP1LMNA | |
| SCHEMBL11318980 | 0.83 | HDAC1 (0.44) | TSHRSMN1; SMN2ALDH1A1TDP1CHRM1 | |
| SCHEMBL4815365 | 0.81 | TSHR (0.39) | TSHRSMN1; SMN2ALDH1A1TDP1CHRM1 | |
| SCHEMBL25735227 | 0.81 | ALDH1A1 (0.36) | TSHRSMN1; SMN2ALDH1A1LMNASLC15A2 | |
| SCHEMBL8011644 | 0.81 | CNR1 (0.40) | TSHRSMN1; SMN2ALDH1A1TDP1CHRM1 | |
| SCHEMBL514688 | 0.81 | — | — | |
| SCHEMBL7225012 | 0.78 | TSHR (0.55) | TSHRSMN1; SMN2TDP1CYP3A4CTSK | |
| SCHEMBL29004671 | 0.78 | TSHR (0.44) | TSHRSMN1; SMN2ALDH1A1LMNACTSK | |
| SCHEMBL8002896 | 0.76 | TSHR (0.48) | TSHRSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL3043590 | 0.76 | L3MBTL1 (0.45) | TSHRSMN1; SMN2ALDH1A1TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378383-B2 | Perfuming ingredients of the woody type | FIRMENICH SA (CH) | 2008-05-27 | — | — | US | disclosed |
| EP-1605035-B1 | Perfuming ingredients of the woody type | FIRMENICH & CIE (CH) | 2007-09-19 | — | — | EP | disclosed |
| EP-1605035-A1 | Perfuming ingredients of the woody type | FIRMENICH SA (CH) | 2005-12-14 | — | — | EP | disclosed |
| US-20050272632-A1 | Perfuming ingredients of the woody type | FIRMENICH SA (CH) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272632-A1 | Perfuming ingredients of the woody type | QDPR, DCXR, CBR3 | TSHR 4145/4885SMN1; SMN2 3841/4885ALDH1A1 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.