⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820834 | 1.00 | — | — | |
| SCHEMBL9732534 | 0.81 | — | — | |
| SCHEMBL9732543 | 0.81 | — | — | |
| SCHEMBL4820807 | 0.75 | — | — | |
| SCHEMBL571056 | 0.74 | RIPK1 (0.35) | — | |
| SCHEMBL2115374 | 0.70 | MMP8 (0.31) | — | |
| SCHEMBL2115371 | 0.70 | MMP8 (0.31) | — | |
| SCHEMBL6178484 | 0.69 | ACACB (0.32) | — | |
| SCHEMBL9927498 | 0.69 | MAPK1 (0.36) | — | |
| SCHEMBL1723602 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365174-B2 | Azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20070042974-A1 | Nozel azalide and azalactam derivatives and method for producing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-22 | — | — | US | disclosed |
| EP-1661904-A1 | NOVEL AZALIDE AND AZALACTAM DERIVATIVES AND PROCESS FOR THE PRODUCTION OF THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |