SCHEMBL4821142

SCHEMBL4821142

Brc1ccc(-c2ccc3ccc4cccc5ccc2c3c45)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HPGD P15428 4/20 0.44
HSD17B10 Q99714 3/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 4/20 0.42
CYP1A1 P04798 2/20 0.42
CYP1B1 Q16678 2/20 0.42
GUSB P08236 1/20 0.42
ERBB2 P04626 1/20 0.41
FYN P06241 1/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
AHR P35869 1/20 0.41
THRB P10828 1/20 0.40
ADORA3 P0DMS8 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12745151 0.90 GUSB (0.40) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL29547734 0.90 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL29512003 0.90 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL2122937 0.90 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL12745153 0.89 GUSB (0.39) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL24282337 0.89 ALDH1A1 (0.52) ALDH1A1TDP1CYP1A2CYP1A1CYP1B1
SCHEMBL16604201 0.89 ALDH1A1 (0.52) ALDH1A1TDP1CYP1A2CYP1A1CYP1B1
SCHEMBL13682552 0.88 CYP1A2 (0.40) ALDH1A1HPGDHSD17B10CYP3A4TSHR
SCHEMBL17940742 0.88 HDAC8 (0.45) ALDH1A1HPGDHSD17B10CYP1A2CYP1A1
SCHEMBL3886375 0.87 CYP1A2 (0.39) ALDH1A1HPGDHSD17B10CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3281238-B1 SEMICONDUCTING MATERIAL COMPRISING A PHOSPHINE OXIDE MATRIX AND METAL SALT NOVALED GMBH (DE) 2024-04-24 EP disclosed
US-11309495-B2 Semiconducting material comprising a phosphine oxide matrix and metal salt NOVALED GMBH (DE) 2022-04-19 US disclosed
US-11296282-B2 Organic compound and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2022-04-05 US disclosed
CN-108101898-B Novel organic electroluminescent compound and organic electroluminescent device comprising same 南京高光半导体材料有限公司 2020-07-14 CN disclosed
US-20200203632-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2020-06-25 US disclosed
CN-107438908-B Semiconductor material comprising phosphine oxide matrix and metal salt 诺瓦尔德股份有限公司 2019-06-18 CN disclosed
CN-108101898-A A kind of novel electroluminescent compound and include its organic electroluminescence device 南京高光半导体材料有限公司 2018-06-01 CN disclosed
US-20180114914-A1 Semiconducting Material Comprising a Phosphine Oxide Matrix and Metal Salt NOVALED GMBH (DE) 2018-04-26 US disclosed
EP-3281238-A1 SEMICONDUCTING MATERIAL COMPRISING A PHOSPHINE OXIDE MATRIX AND METAL SALT Novaled GmbH (DE) 2018-02-14 EP disclosed
CN-107438908-A Semi-conducting material comprising phosphine oxide matrix and metal salt 诺瓦尔德股份有限公司 2017-12-05 CN disclosed
US-7361796-B2 Orangic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2008-04-22 US disclosed
US-20070237982-A1 Polycyclic Aromatic Compound, Material for Forming Luminescent Coating Film and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US disclosed
US-20070237982-A1 Polycyclic Aromatic Compound, Material for Forming Luminescent Coating Film and Organic Electroluminescent Device Using Same IDEMITSU KOSAN CO., LTD. (JP) 2007-10-11 US disclosed
EP-1780191-A1 FLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-05-02 EP disclosed
EP-1762553-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR FORMING LUMINESCENT COATING FILM AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-03-14 EP disclosed
US-7053255-B2 Substituted diphenylanthracene compounds for organic electroluminescence devices IDEMITSU KOSAN CO., LTD. (JP) 2006-05-30 US disclosed
US-20060083947-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2006-04-20 US disclosed
US-20040214035-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. 2004-10-28 US disclosed
EP-1333018-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2003-08-06 EP disclosed
CN-1394195-A Organic electroluminescent element IDEMITSU KOSAN CO (JP) 2003-01-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11296282-B2 Organic compound and organic electroluminescence device using the same SLCO4C1, EML4, SLCO2A1 ALDH1A1 386/4885HPGD 3474/4885HSD17B10 2422/4885
US-11309495-B2 Semiconducting material comprising a phosphine oxide matrix and metal salt C1S, C5, SLC26A3 ALDH1A1 2484/4885HPGD 4000/4885HSD17B10 1765/4885
US-20200203632-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME SLCO4C1, EML4, SLCO2A1 ALDH1A1 386/4885HPGD 3474/4885HSD17B10 2422/4885
US-20180114914-A1 Semiconducting Material Comprising a Phosphine Oxide Matrix and Metal Salt C1S, C5, SLC26A3 ALDH1A1 2484/4885HPGD 4000/4885HSD17B10 1765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.