Sugi Predict

Sugi Predict / Compounds / SCHEMBL482233

SCHEMBL482233

SCHEMBL482233

Nc1nc2cc([N+](=O)[O-])ccc2s1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.77
▸ TDP1 Q9NUW8 2/20 0.77
▸ CYP3A4 P08684 1/20 0.77
▸ TSHR P16473 1/20 0.77
▸ GAA P10253 2/20 0.55
▸ RIPK1 Q13546 1/20 0.52
▸ ACP1 P24666 1/20 0.50
▸ HTT P42858 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ CA2 P00918 1/20 0.49
▸ CA5A P35218 1/20 0.49
▸ PDK1 Q15118 1/20 0.49
▸ TXNRD1 Q16881 1/20 0.49
▸ TXNRD3 Q86VQ6 1/20 0.49
▸ TXNRD2 Q9NNW7 1/20 0.49
▸ PIK3CD O00329 1/20 0.47
▸ PIK3CA P42336 1/20 0.47
▸ PIK3CB P42338 1/20 0.47
▸ PIK3CG P48736 1/20 0.47
▸ MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31219335 1.00 ALDH1A1 (0.77) ALDH1A1TDP1CYP3A4TSHRGAA
SCHEMBL334808 0.87 ALDH1A1 (1.00) ALDH1A1TDP1CYP3A4TSHRGAA
SCHEMBL2172967 0.87 SMN1; SMN2 (0.75) ALDH1A1TDP1CYP3A4TSHRGAA
Nitrogen SCHEMBL28651597 0.84 ALDH1A1 (0.94) ALDH1A1TDP1CYP3A4TSHRGAA
SCHEMBL5049722 0.83 ALDH1A1 (0.86) ALDH1A1TDP1CYP3A4TSHRGAA
SCHEMBL23926457 0.81 RIPK1 (0.53) ALDH1A1TDP1CYP3A4TSHRRIPK1
Sulfuric Acid SCHEMBL28206216 0.80 ALDH1A1 (0.86) ALDH1A1TDP1CYP3A4TSHRGAA
SCHEMBL29361660 0.80 RIPK1 (0.52) ALDH1A1TDP1CYP3A4TSHRRIPK1
SCHEMBL2002714 0.80 RIPK1 (0.52) ALDH1A1TDP1CYP3A4TSHRRIPK1
SCHEMBL617121 0.80 RIPK1 (0.52) ALDH1A1TDP1CYP3A4TSHRRIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109535044-B Diazotization method of aromatic primary amine 金华双宏化工有限公司 2021-06-15 — — CN claimed
CN-110387141-B Azo cationic reactive dye with dye matrix being benzothiazole, preparation and application thereof 东华大学 2020-12-18 — — CN claimed
CN-101391987-B Two-dimension azo heterocycles chromophores and synthetic method thereof UNIV SOUTHEAST 2011-07-20 — — CN claimed
CN-101391987-A Two-dimension azo heterocycles chromophores and synthetic method thereof UNIV SOUTHEAST (CN) 2009-03-25 — — CN claimed
EP-0100008-A1 Azo dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1984-02-08 — — EP claimed
EP-0087037-A1 Azo-dyestuffs BAYER AG (DE) 1983-08-31 — — EP claimed
CN-121950015-A Carbon fiber reinforced polyether-ether-ketone self-lubricating composite material and preparation method and application thereof 中国科学院兰州化学物理研究所 2026-05-01 — — CN disclosed
EP-4289830-B1 NLRP3 INFLAMMASOME SMALL-MOLECULE INHIBITOR FOR TREATMENT OF ALZHEIMER'S DISEASE UNIV AJOU IND ACADEMIC COOP FOUND (KR) 2026-04-08 — — EP disclosed
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 — — US disclosed
CN-119707861-A 2-Substituted aminobenzothiazole compound and application thereof 沈阳药科大学 2025-03-28 — — CN disclosed
WO-2025031129-A1 ARYL UREA DERIVATIVE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF 沈阳药科大学 2025-02-13 — — WO disclosed
CN-118359602-A Aryl urea derivative and application thereof 沈阳药科大学 2024-07-19 — — CN disclosed
EP-4008790-B1 MONOAZO DYES WITH CYCLIC AMINE AS FLUORESCENCE QUENCHERS ENZO BIOCHEM INC (US) 2024-07-17 — — EP disclosed
EP-0025190-B1 CHROMOGENIC COMPOUNDS AND THEIR USE AS ENZYMATIC SUBSTRATES BEHRINGWERKE Aktiengesellschaft (DE) 1984-06-13 — — EP disclosed
EP-0100008-A1 Azo dyestuffs, their preparation and their use CASSELLA Aktiengesellschaft (DE) 1984-02-08 — — EP disclosed
EP-0087037-A1 Azo-dyestuffs BAYER AG (DE) 1983-08-31 — — EP disclosed
EP-0039835-B1 PROCESS FOR THE PREPARATION OF 2-AMINO-6-NITRO-BENZOTHIAZOLE BAYER AG (DE) 1983-03-09 — — EP disclosed
US-4369324-A Process for the preparation of 2-amino-6-nitrobenzothiazole BAYER AKTIENGESELLSCHAFT (DE) 1983-01-18 — — US disclosed
EP-0039835-A1 Process for the preparation of 2-amino-6-nitro-benzothiazole BAYER AG (DE) 1981-11-18 — — EP disclosed
EP-0025190-A2 Chromogenic compounds and their use as enzymatic substrates BEHRINGWERKE Aktiengesellschaft (DE) 1981-03-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12590071-B2 Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof ABL1, TH, CYP3A43 ALDH1A1 1008/4885TDP1 2058/4885CYP3A4 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.