SCHEMBL482240

SCHEMBL482240

Fc1cccc(Sc2cccc(F)c2)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.55
ACHE P22303 1/20 0.46
NFE2L2 Q16236 3/20 0.44
NOTUM Q6P988 1/20 0.42
EPHX1 P07099 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
PKM P14618 1/20 0.39
MAPK1 P28482 1/20 0.39
THPO P40225 1/20 0.39
NPC1 O15118 1/20 0.39
CHRM5 P08912 1/20 0.39
GRM5 P41594 1/20 0.39
RAB9A P51151 1/20 0.39
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
TYMS P04818 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775416 0.93 HAO1 (0.50) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL7938436 0.91 HAO1 (0.49) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL10546679 0.87 HAO1 (0.46) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL22693473 0.87 HAO1 (0.46) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL24156265 0.85 CYP3A4 (0.56) HAO1EPHX1CYP3A4MAPK1TYMS
SCHEMBL5685309 0.85 HAO1 (0.45) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL577210 0.83 ACHE (0.46) HAO1ACHENFE2L2EPHX1CES2
SCHEMBL19628602 0.82 HAO1 (0.42) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL9685565 0.82 HAO1 (0.46) HAO1ACHENFE2L2NOTUMEPHX1
SCHEMBL11200483 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504523-A Preparation method of fluorine-containing phenyl sulfoxide compound 苏州源起材料科技有限公司 2025-02-25 CN disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20240297344-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-05 US disclosed
CN-117567332-A Method for simultaneously synthesizing thioether compounds and nitrile compounds 石河子大学 2024-02-20 CN disclosed
WO-2023067915-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMATION METHOD JSR株式会社 2023-04-27 WO disclosed
CN-115911573-A Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery using same 三菱化学株式会社 2023-04-04 CN disclosed
US-11616253-B2 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2023-03-28 US disclosed
WO-2023032973-A1 RADIATION-SENSITIVE RESIN COMPOSITION AND PATTERN FORMATION METHOD JSR株式会社 2023-03-09 WO disclosed
US-20220278370-A1 NONAQUEOUS ELECTROLYTE FOR SECONDARY BATTERY AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERY EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2022-09-01 US disclosed
US-11367899-B2 Nonaqueous electrolyte for secondary battery and nonaqueous-electrolyte secondary battery employing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-21 US disclosed
EP-0162606-B1 AROMATIC POLYTHIOETHERAMIDES AND PROCESS FOR THEIR PRODUCTION MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-01-25 EP disclosed
EP-0135938-B1 PROCESS FOR PRODUCING AROMATIC POLYETHER KETONES AND POLYTHIOETHER KETONES MITSUBISHI KASEI CORPORATION (JP) 1988-06-22 EP disclosed
US-4707536-A Catalytic preparation of aromatic polyketone from phosgene and aromatic ether or sulfide MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-11-17 US disclosed
US-4661581-A REACTING AROMATIC ETHERS OR THIOETHERS WITH PHOSGENE IN AN APROTIC SOLVENT WITH GROUP 3 METAL HALIDE CATALYST MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1987-04-28 US disclosed
US-4621134-A Aromatic polythioetheramide MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1986-11-04 US disclosed
EP-0162606-A1 Aromatic polythioetheramides and process for their production MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1985-11-27 EP disclosed
US-4533497-A N-ethylidene azetidinones ELI LILLY AND COMPANY (US) 1985-08-06 US disclosed
EP-0135938-A2 Process for producing aromatic polyether ketones and polythioether ketones MITSUBISHI KASEI CORPORATION (JP) 1985-04-03 EP disclosed
US-4339611-A BUTANOL, BUTANAL, COBALT, IODINE GULF RESEARCH & DEVELOPMENT COMPANY (US) 1982-07-13 US disclosed
US-3939084-A Functional fluid compositions containing substituted pyrimidines MONSANTO COMPANY (US) 1976-02-17 US disclosed