SCHEMBL7938436

SCHEMBL7938436

Fc1ccc(Sc2cccc(F)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.49
NFE2L2 Q16236 2/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 1/20 0.42
MGLL Q99685 1/20 0.40
ACHE P22303 1/20 0.39
ANXA2 P07355 1/20 0.39
S100A10 P60903 1/20 0.39
NOTUM Q6P988 1/20 0.39
MAOA P21397 2/20 0.38
MAOB P27338 2/20 0.38
EPHX1 P07099 1/20 0.38
HTR2C P28335 1/20 0.37
HTR6 P50406 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
DHFR P00374 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482240 0.91 HAO1 (0.55) HAO1NFE2L2ACHENOTUMEPHX1
SCHEMBL775416 0.88 HAO1 (0.50) HAO1NFE2L2MGLLACHENOTUM
SCHEMBL24156265 0.85 CYP3A4 (0.56) HAO1MEN1KMT2AMAPTMGLL
SCHEMBL22693473 0.83 HAO1 (0.46) HAO1NFE2L2MGLLACHENOTUM
SCHEMBL5685309 0.81 HAO1 (0.45) HAO1NFE2L2MGLLACHEANXA2
SCHEMBL3967111 0.81 MAOB (0.42) MEN1KMT2AMAPTANXA2S100A10
SCHEMBL10549354 0.81 MEN1 (0.39) HAO1MEN1KMT2AMAPTMGLL
SCHEMBL14045278 0.81 ACHE (0.50) MEN1KMT2AMAPTMGLLACHE
SCHEMBL4705053 0.81 NFE2L2 (0.51) HAO1NFE2L2MAPTMAOBHTR2C
SCHEMBL11980111 0.80 MAOA (0.50) NFE2L2MEN1KMT2AMAPTMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023176680-A1 COMPOSITION AND CURED PRODUCT 株式会社ADEKA 2023-09-21 WO disclosed
WO-2017170881-A9 CURABLE COMPOSITION, CURED PRODUCT PRODUCTION METHOD, AND CURED PRODUCT THEREFROM 株式会社ADEKA 2021-04-01 WO disclosed
WO-2020045358-A1 COMPOSITION, ADHESIVE INCLUDING SAME, CURED OBJECT OBTAINED THEREFROM, AND PRODUCTION METHOD THEREFOR 株式会社ADEKA 2020-03-05 WO disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed