SCHEMBL5685309

SCHEMBL5685309

Fc1cccc(Sc2cc[c]cc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HAO1 Q9UJM8 1/20 0.45
NOTUM Q6P988 1/20 0.36
ACHE P22303 1/20 0.35
MGLL Q99685 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
EPHX1 P07099 1/20 0.35
NFE2L2 Q16236 1/20 0.34
HTR2C P28335 1/20 0.34
HTR6 P50406 1/20 0.34
TYMS P04818 1/20 0.33
ANXA2 P07355 1/20 0.33
S100A10 P60903 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
MAPK13 O15264 1/20 0.32
MAPK12 P53778 1/20 0.32
MAPK11 Q15759 1/20 0.32
MAPK14 Q16539 1/20 0.32
SLC6A9 P48067 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL482240 0.85 HAO1 (0.55) HAO1NOTUMACHEEPHX1NFE2L2
SCHEMBL775416 0.83 HAO1 (0.50) HAO1NOTUMACHEMGLLMAOA
SCHEMBL7938436 0.81 HAO1 (0.49) HAO1NOTUMACHEMGLLMAOA
SCHEMBL9685565 0.81 HAO1 (0.46) HAO1NOTUMACHEMGLLMAOA
SCHEMBL5685447 0.76 MEN1 (0.40) ACHEMAOAMAOB
SCHEMBL24156265 0.76 CYP3A4 (0.56) HAO1MGLLMAOBEPHX1HTR2C
SCHEMBL922044 0.76 ACHE (0.42) NOTUMACHEMGLLMAOAMAOB
SCHEMBL5685180 0.76 MAOA (0.40) MAOAMAOBHTR2CHTR6TYMS
SCHEMBL694068 0.76 POLB (0.50) NOTUMMAOAMAOB
SCHEMBL4612800 0.76 ANXA2 (0.43) MAOAMAOBHTR2CHTR6ANXA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060122064-A1 Amides and method for plant diseases control with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 US disclosed
EP-1640360-A1 AMIDES AND METHOD FOR PLANT DISEASE CONTROL WITH THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122064-A1 Amides and method for plant diseases control with the same ARG1, ARGLU1, ARG2 HAO1 1047/4885NOTUM 570/4885ACHE 742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.