Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336584 | 1.00 | AOC3 (0.45) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL3337325 | 1.00 | AOC3 (0.45) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL3336585 | 1.00 | AOC3 (0.45) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL16680070 | 0.84 | MEN1 (0.47) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL499618 | 0.82 | AOC3 (0.42) | AOC3SLC6A2SLC6A4TSHRRECQL | |
| SCHEMBL499093 | 0.82 | AOC3 (0.42) | AOC3SLC6A2SLC6A4TSHRRECQL | |
| SCHEMBL16680515 | 0.80 | GBA1 (0.53) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| Oxalic Acid SCHEMBL27380050 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDTRPM8 | |
| SCHEMBL499094 | 0.73 | TRPM8 (0.39) | AOC3SLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL499619 | 0.73 | TRPM8 (0.39) | AOC3SLC6A2SLC6A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156816-A2 | RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-12-24 | — | — | WO | disclosed |