Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336584 | 1.00 | AOC3 (0.45) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL3337325 | 1.00 | AOC3 (0.45) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL4822741 | 1.00 | AOC3 (0.45) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL16680070 | 0.84 | MEN1 (0.47) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL499618 | 0.82 | AOC3 (0.42) | AOC3SLC6A2SLC6A4TSHRRECQL | |
| SCHEMBL499093 | 0.82 | AOC3 (0.42) | AOC3SLC6A2SLC6A4TSHRRECQL | |
| SCHEMBL16680515 | 0.80 | GBA1 (0.53) | AOC3MEN1KMT2ASLC6A2SLC6A4 | |
| Oxalic Acid SCHEMBL27380050 | 0.74 | MEN1 (0.49) | MEN1KMT2AALDH1A1HPGDTRPM8 | |
| SCHEMBL499094 | 0.73 | TRPM8 (0.39) | AOC3SLC6A2SLC6A4KDM4EALDH1A1 | |
| SCHEMBL499619 | 0.73 | TRPM8 (0.39) | AOC3SLC6A2SLC6A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144825-A1 | Renin Inhibitors | VITAE PHARMACEUTICALS, INC. | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144825-A1 | Renin Inhibitors | ACE, REN, DNPEP | AOC3 2000/4885MEN1 2445/4885KMT2A 3830/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.