Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.37 |
| ▸ | CHRNG | P07510 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.37 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499094 | 1.00 | TRPM8 (0.39) | TRPM8GAANPY5RSLC6A2SLC6A4 | |
| SCHEMBL3336585 | 0.73 | AOC3 (0.45) | TRPM8SLC6A2SLC6A4AOC3KDM4E | |
| SCHEMBL4822741 | 0.73 | AOC3 (0.45) | TRPM8SLC6A2SLC6A4AOC3KDM4E | |
| SCHEMBL3337325 | 0.73 | AOC3 (0.45) | TRPM8SLC6A2SLC6A4AOC3KDM4E | |
| SCHEMBL3336584 | 0.73 | AOC3 (0.45) | TRPM8SLC6A2SLC6A4AOC3KDM4E | |
| SCHEMBL28951519 | 0.71 | ACP3 (0.46) | SLC6A2SLC6A4ACP3LMNAHIF1A | |
| SCHEMBL29403128 | 0.69 | ACP3 (0.50) | SLC6A2SLC6A4ACP3LMNAAOC3 | |
| SCHEMBL11606577 | 0.69 | ACP3 (0.50) | SLC6A2SLC6A4ACP3LMNAAOC3 | |
| Oxalic Acid SCHEMBL27380050 | 0.69 | MEN1 (0.49) | TRPM8ACP3ALDH1A1HPGDADRB2 | |
| SCHEMBL11291446 | 0.69 | MEN1 (0.50) | TRPM8ACP3LMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106221-B2 | Renin inhibitors | VITAE PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |