Diphenylmethane

Diphenylmethane

SCHEMBL4823726

O=C(O)c1cc(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1C(=O)O.O=C(O)c1cc(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1C(=O)O.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 7/20 0.56
PTPN2 P17706 3/20 0.51
PTPN6 P29350 3/20 0.51
ACMSD Q8TDX5 2/20 0.48
HNF4A P41235 2/20 0.46
FOLH1 Q04609 2/20 0.44
PLA2G2A P14555 2/20 0.42
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
KMT2A Q03164 1/20 0.40
PLA2G10 O15496 1/20 0.39
CDC25B P30305 1/20 0.39
ATM Q13315 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL6129045 1.00 PTPN1 (0.56) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL50362 0.91 HNF4A (0.50) PTPN1PTPN2PTPN6ACMSDHNF4A
Diphenylether SCHEMBL6129070 0.82 GSTP1 (0.44) PTPN1HNF4AMEN1KMT2AAKR1C3
SCHEMBL10695933 0.78 PTPN1 (0.57) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL29443090 0.77 HNF4A (0.50) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL8459682 0.77 HNF4A (0.50) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL28410944 0.77 HNF4A (0.53) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL247392 0.76 HNF4A (0.46) PTPN1PTPN2PTPN6ACMSDHNF4A
SCHEMBL988420 0.76 MCL1 (0.47) MEN1ALDH1A1GAAKMT2AAKR1C3
SCHEMBL830012 0.76 ALDH1A1 (0.48) PTPN1ACMSDHNF4AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396898-B2 Diamine, acid dianhydride, and reactive group containing polyimide composition prepared therefrom and process of preparing them KANEKA CORPORATION (JP) 2008-07-08 US disclosed
US-20040158030-A1 Diamine, acid dianhydride, polymide composition having reactive group obtained therefrom, and processes for producing these KANEKA CORPORATION (JP) 2004-08-12 US disclosed