SCHEMBL4824404

SCHEMBL4824404

O=C1OC2(c3ccc(O)cc3Oc3cc(O)cc(F)c32)c2c(F)c(F)c(F)c(F)c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.53
ALOX12 P18054 2/20 0.53
ALDH1A1 P00352 2/20 0.53
CYP2C9 P11712 1/20 0.53
ALOX15 P16050 1/20 0.53
BRCA1 P38398 1/20 0.53
HSD17B10 Q99714 1/20 0.53
FTO Q9C0B1 10/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
HTT P42858 2/20 0.49
SMAD3 P84022 2/20 0.49
CYP2C19 P33261 1/20 0.49
RECQL P46063 1/20 0.49
BLM P54132 1/20 0.49
PRMT1 Q99873 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1065103 0.91 HPGD (0.53) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL1608876 0.90 HPGD (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
Hydrochloric Acid SCHEMBL25316086 0.89 HPGD (0.62) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL6535975 0.84 HPGD (0.51) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL7960297 0.81 HPGD (0.58) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL29565097 0.80 FTO (0.74) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL4576798 0.79 FTO (0.58) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL6637206 0.78 ALDH1A1 (0.55) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL5052755 0.78 FTO (0.63) HPGDALOX12ALDH1A1CYP2C9ALOX15
SCHEMBL601176 0.78 FTO (0.59) HPGDALOX12ALDH1A1CYP2C9ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7332356-B2 Fluorescent dye binding peptides THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2008-02-19 US disclosed
US-20040176578-A1 Fluorescent dye binding peptides THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2004-09-09 US disclosed
US-6747135-B1 Fluorescent dye binding peptides THE BOARD OF TRUSTEES FOR THE LELAND STANFORD JUNIOR UNIVERSITY 2004-06-08 US disclosed
WO-2000023463-A9 FLUORESCENT DYE BINDING PEPTIDES UNIV LELAND STANFORD JUNIOR (US) 2001-07-05 WO disclosed
WO-2000023463-A2 FLUORESCENT DYE BINDING PEPTIDES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2000-04-27 WO disclosed