Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMAD3 | P84022 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824404 | 0.91 | HPGD (0.53) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL1608876 | 0.90 | HPGD (0.63) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| Hydrochloric Acid SCHEMBL25316086 | 0.89 | HPGD (0.62) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL29469745 | 0.83 | FTO (0.71) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL7960297 | 0.81 | HPGD (0.58) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL7970057 | 0.80 | HPGD (0.54) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL6637206 | 0.78 | ALDH1A1 (0.55) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL1644389 | 0.78 | HPGD (0.41) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL4576798 | 0.77 | FTO (0.58) | HPGDALOX12ALDH1A1CYP2C9ALOX15 | |
| SCHEMBL1608886 | 0.76 | HPGD (0.45) | HPGDALOX12ALDH1A1CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311261-B1 | MEDICAMENTS FOR CHEMOTHERAPEUTIC TREATMENT OF DISEASE | PHOTOGEN INC (US) | 2008-01-23 | — | — | EP | claimed |
| EP-1292298-B1 | INTRACORPOREAL MEDICAMENTS FOR HIGH ENERGY PHOTOTHERAPEUTIC TREATMENT OF DISEASE | PHOTOGEN INC (US) | 2007-03-28 | — | — | EP | claimed |
| EP-1210078-A4 | IMPROVED TOPICAL MEDICAMENTS AND METHODS FOR PHOTODYNAMIC TREATMENT OF DISEASE | PHOTOGEN INC (US) | 2004-06-09 | — | — | EP | claimed |
| EP-1284727-A1 | INTRACORPOREAL MEDICAMENTS FOR PHOTODYNAMIC TREATMENT OF DISEASE | Photogen, Inc. (US) | 2003-02-26 | — | — | EP | claimed |
| EP-1210078-A1 | IMPROVED TOPICAL MEDICAMENTS AND METHODS FOR PHOTODYNAMIC TREATMENT OF DISEASE | Photogen, Inc. (US) | 2002-06-05 | — | — | EP | claimed |
| WO-2001072301-A1 | INTRACORPOREAL MEDICAMENTS FOR PHOTODYNAMIC TREATMENT OF DISEASE | PHOTOGEN, INC. (US) | 2001-10-04 | — | — | WO | claimed |
| WO-2001012181-A1 | IMPROVED TOPICAL MEDICAMENTS AND METHODS FOR PHOTODYNAMIC TREATMENT OF DISEASE | PHOTOGEN, INC. (US) | 2001-02-22 | — | — | WO | claimed |
| WO-2017153593-A1 | PH-RESPONSIVE POLY-NUCLEIC ACID COMPLEXES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2017-09-14 | — | — | WO | disclosed |
| US-8057997-B2 | Nucleic acid binding compounds containing pyrazolo[3,4-D]pyrimidine analogues of purin-2,6-diamine and their uses | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20110021365-A1 | Nucleic Acid Binding Compounds Containing Pyrazolo[3,4-D]Pyrimidine Analogues of Purin-2,6-Diamine and Their Uses | ROCHE MOLECULAR SYSTEMS, INC. | 2011-01-27 | — | — | US | disclosed |
| US-7847075-B2 | 2-Azapurine compounds and their use | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2010-12-07 | — | — | US | disclosed |
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | ROCHE DIAGNOSTICS GMBH (DE) | 2010-11-18 | — | — | US | disclosed |
| US-20090306360-A1 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ROCHE MOLECULAR SYSTEMS, INC. (US) | 2009-12-10 | — | — | US | disclosed |
| WO-2001072764-A1 | N?8- AND C8¿-LINKED PURINE BASES AND STRUCTURALLY RELATED HETEROCYCLES AS UNIVERSAL NUCLEOSIDES USED FOR OLIGONUCLEOTIDE HYBRIDIZATION | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001072301-A1 | INTRACORPOREAL MEDICAMENTS FOR PHOTODYNAMIC TREATMENT OF DISEASE | PHOTOGEN, INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| US-6251615-B1 | Cell analysis methods | CELL ANALYTICS, INC. | 2001-06-26 | — | — | US | disclosed |
| WO-2001016149-A2 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ROCHE DIAGNOSTICS GMBH (DE) | 2001-03-08 | — | — | WO | disclosed |
| EP-1057004-A1 | CELL ANALYSIS METHODS AND APPARATUS | Sanguinex (US) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999042809-A9 | CELL ANALYSIS METHODS AND APPARATUS | SANGUINEX (US) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999042809-A1 | CELL ANALYSIS METHODS AND APPARATUS | SANGUINEX (US) | 1999-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306360-A1 | 2-AZAPURINE COMPOUNDS AND THEIR USE | ADAR, AMPD2, NSUN2 | HPGD 3024/4885ALOX12 3714/4885ALDH1A1 2276/4885 |
| US-20100290992-A1 | NANOPARTICLE NUCLEIC ACID BINDING COMPOUND CONJUGATES FORMING I-MOTIFS | POLM, IGF2BP1, POLRMT | HPGD 4341/4885ALOX12 4630/4885ALDH1A1 1225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.