SCHEMBL48248

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Oxalic Acid SCHEMBL48280	0.94	SIGMAR1 (0.66)	SIGMAR1HCRTR1HCRTR2OPRM1OPRK1
	SCHEMBL14492378	0.89	SIGMAR1 (0.76)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4
	SCHEMBL52099	0.88	SIGMAR1 (0.70)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4
	SCHEMBL48105	0.86	SIGMAR1 (0.66)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4
	SCHEMBL48619	0.85	SIGMAR1 (0.79)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4
	SCHEMBL48135	0.85	SIGMAR1 (0.69)	SIGMAR1CYP2A6SLC6A4SLC6A3SLC6A2
	SCHEMBL47955	0.83	SIGMAR1 (0.70)	SIGMAR1HCRTR1HCRTR2SLC6A4SLC6A3
	SCHEMBL48405	0.83	SIGMAR1 (0.69)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4
	SCHEMBL48025	0.83	SIGMAR1 (0.72)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4
	T-817 SCHEMBL27725	0.83	SIGMAR1 (1.00)	SIGMAR1CYP2A6HCRTR1HCRTR2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.