Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48248 | 0.88 | SIGMAR1 (0.70) | SIGMAR1CYP2A6SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14492378 | 0.87 | SIGMAR1 (0.76) | SIGMAR1HRH3CYP2A6SLC6A4SLC6A3 | |
| SCHEMBL48619 | 0.85 | SIGMAR1 (0.79) | SIGMAR1HRH3CYP2A6SLC6A4SLC6A3 | |
| SCHEMBL48135 | 0.85 | SIGMAR1 (0.69) | SIGMAR1HRH3CYP2A6SLC6A4SLC6A3 | |
| SCHEMBL48405 | 0.85 | SIGMAR1 (0.69) | SIGMAR1HRH3CYP2A6SLC6A4SLC6A3 | |
| SCHEMBL52071 | 0.83 | SIGMAR1 (0.60) | SIGMAR1CYP2A6CA12CA2HCRTR1 | |
| SCHEMBL48025 | 0.83 | SIGMAR1 (0.72) | SIGMAR1CYP2A6SLC6A4SLC6A3SLC6A2 | |
| Oxalic Acid SCHEMBL48280 | 0.83 | SIGMAR1 (0.66) | SIGMAR1HRH3HCRTR1HCRTR2OPRM1 | |
| T-817 SCHEMBL27725 | 0.83 | SIGMAR1 (1.00) | SIGMAR1HRH3CYP2A6SLC6A4SLC6A3 | |
| T-817 SCHEMBL30574118 | 0.83 | SIGMAR1 (1.00) | SIGMAR1HRH3CYP2A6SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43676-E1 | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-09-18 | — | — | US | disclosed |
| US-8129535-B2 | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2009-04-30 | — | — | US | disclosed |
| US-7468443-B2 | Alkyl ether derivatives or salts thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111992-A1 | ALKYL ETHER DERIVATIVES OR SALTS THEREOF | AHNAK, NGF, PMP22 | SIGMAR1 1934/4885HRH3 2125/4885CYP2A6 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.