SCHEMBL4824829

SCHEMBL4824829

O=C(OC12C=CC(CC1)C2)c1cccc2cc3ccccc3cc12

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
GAA P10253 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
EPHX1 P07099 1/20 0.31
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4981052 0.89 KMT2A (0.40) KDM4EGAAALDH1A1POLBKMT2A
SCHEMBL28720960 0.68 MAPT (0.67) KDM4EGAAALDH1A1MAPTTDP1
SCHEMBL2464246 0.68 KDM4E (0.68) KDM4EGAAALDH1A1MAPTTDP1
SCHEMBL24943764 0.67 KDM4E (0.43) KDM4EGAAALDH1A1MAPTTDP1
SCHEMBL1164706 0.66 ALDH1A1 (0.61) KDM4EGAAALDH1A1MAPTPOLB
SCHEMBL30163583 0.66 KDM4E (0.61) KDM4EGAAALDH1A1MAPTTDP1
SCHEMBL6757708 0.65 MAPT (0.67) KDM4EGAAALDH1A1MAPTTDP1
SCHEMBL25189907 0.65 ALDH1A1 (0.59) KDM4EGAAALDH1A1MAPTPOLB
SCHEMBL12689815 0.65 KDM4E (0.50) KDM4EGAAALDH1A1MAPTPOLB
SCHEMBL12689787 0.65 KDM4E (0.42) KDM4EGAAALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7400371-B2 Liquid crystal display having particular retardation plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-07-15 US disclosed
US-7365815-B2 Phase retardation film and liquid crystal display device including the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-04-29 US disclosed
US-20050280758-A1 Phase retardation film and liquid crystal display device including the same SUMITOMO CHEMICAL COMPANY, LIMITED 2005-12-22 US disclosed
EP-1607774-A1 Phase retardation film and liquid crystal display device including the same Sumitomo Chemical Company, Limited (JP) 2005-12-21 EP disclosed
US-20050185124-A1 Liquid crystal display SUMITOMO CHEMICAL COMPANY, LIMITED 2005-08-25 US disclosed