SCHEMBL4981052

SCHEMBL4981052

O=C(OC12C=CC(CC1)C2)c1cccc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
NR4A1 P22736 1/20 0.39
NR4A2 P43354 1/20 0.39
NR4A3 Q92570 1/20 0.39
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 2/20 0.36
MMP3 P08254 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
CDC25B P30305 2/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
HPGD P15428 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
PTPN1 P18031 1/20 0.35
PLK1 P53350 1/20 0.35
MEN1 O00255 2/20 0.35
RAB9A P51151 1/20 0.35
ATM Q13315 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4824829 0.89 KDM4E (0.42) KMT2APOLBGAAKDM4EALDH1A1
SCHEMBL7716682 0.72 KMT2A (0.39) KMT2APOLBGAANR4A1NR4A2
SCHEMBL7600356 0.70 ALDH1A1 (0.41) KMT2APOLBGAANR4A1NR4A2
SCHEMBL2899391 0.69 KMT2A (0.42) KMT2APOLBGAANR4A1NR4A2
SCHEMBL28847733 0.69 HPGD (0.47) KMT2APOLBGAANR4A1NR4A2
SCHEMBL2117154 0.68 KMT2A (0.53) KMT2APOLBGAANR4A1NR4A2
SCHEMBL9542149 0.68 KMT2A (0.55) KMT2APOLBGAANR4A1NR4A2
SCHEMBL6560064 0.68 KMT2A (0.50) KMT2APOLBGAAKDM4EALDH1A1
SCHEMBL2119946 0.67 KMT2A (0.56) KMT2APOLBGAANR4A1NR4A2
SCHEMBL4404102 0.66 NR4A1 (0.59) KMT2APOLBGAANR4A1NR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7365815-B2 Phase retardation film and liquid crystal display device including the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-04-29 US disclosed
US-20050280758-A1 Phase retardation film and liquid crystal display device including the same SUMITOMO CHEMICAL COMPANY, LIMITED 2005-12-22 US disclosed
EP-1607774-A1 Phase retardation film and liquid crystal display device including the same Sumitomo Chemical Company, Limited (JP) 2005-12-21 EP disclosed
US-20050185124-A1 Liquid crystal display SUMITOMO CHEMICAL COMPANY, LIMITED 2005-08-25 US disclosed