Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4825098 | 0.73 | ALDH1A1 (0.37) | KMT2ACYP1A2SMN1; SMN2MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28202421 | 0.71 | KMT2A (0.41) | KMT2ACYP1A2SMN1; SMN2MEN1PKM | |
| SCHEMBL23400990 | 0.63 | ALDH1A1 (0.35) | KMT2ACYP1A2ALDH1A1MAPTKDM4E | |
| SCHEMBL3197855 | 0.61 | KMT2A (0.40) | KMT2ACYP1A2SMN1; SMN2MEN1PKM | |
| SCHEMBL20159610 | 0.60 | HPGD (0.36) | KMT2ACYP1A2SMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL28203964 | 0.60 | SMN1; SMN2 (0.37) | CYP1A2SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL31661272 | 0.57 | KMT2A (0.50) | KMT2ACYP1A2SMN1; SMN2MEN1PKM | |
| SCHEMBL3402379 | 0.55 | SMN1; SMN2 (0.37) | KMT2ACYP1A2SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28202073 | 0.55 | SMN1; SMN2 (0.37) | KMT2ASMN1; SMN2ALDH1A1KDM4EPOLB | |
| Bromide SCHEMBL27981879 | 0.55 | SMN1; SMN2 (0.37) | KMT2ASMN1; SMN2ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446105-B2 | Pyrimidine compounds | ASTRAZENECA AB (SE) | 2008-11-04 | — | — | US | disclosed |
| US-20050119291-A1 | Pyrimidine compounds | ASTRAZENECA AB (SE) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119291-A1 | Pyrimidine compounds | TYMP, TYMS, CCNT1 | KMT2A 3174/4885CYP1A2 1733/4885SMN1; SMN2 2553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.