SCHEMBL482707

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2032564	0.89	LMNA (0.52)	LMNAALDH1A1KDM4ERAB9A
	SCHEMBL481831	0.85	APP (0.52)	CA12CA1CA2TYRCA7
	SCHEMBL2708790	0.85	ABCG2 (0.49)	CA12CA1CA2TYRCA7
	SCHEMBL8043549	0.84	TYR (0.53)	CA12CA1CA2TYRCA7
	SCHEMBL3700257	0.83	LMNA (0.50)	CA12CA1CA2TYRCA7
	SCHEMBL3469080	0.83	LMNA (0.53)	LMNAALDH1A1KDM4EMEN1KMT2A
	SCHEMBL482027	0.82	TYR (0.50)	CA12CA1CA2TYRCA7
	SCHEMBL8138457	0.81	ALDH1A1 (0.56)	LMNAALDH1A1MAPTKDM4ERAB9A
	SCHEMBL2707312	0.81	LMNA (0.50)	CA12CA1CA2TYRCA7
	SCHEMBL11523182	0.78	LMNA (0.50)	LMNAALDH1A1KDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.