Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561783 | 0.90 | HTT (0.53) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL4820408 | 0.88 | TGM2 (0.47) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL6563172 | 0.87 | HTT (0.50) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL9874334 | 0.83 | HTT (0.79) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL15346534 | 0.83 | HTT (0.79) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL9340146 | 0.83 | HTT (0.79) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL7877730 | 0.81 | HTT (0.72) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL18254066 | 0.81 | HTT (0.81) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL6561674 | 0.81 | SMN1; SMN2 (0.47) | TGM2HTTLMNASMN1; SMN2KEAP1 | |
| SCHEMBL6563145 | 0.80 | LMNA (0.46) | TGM2HTTLMNASMN1; SMN2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323596-B2 | Antibacterial or antiprotozoal activity: formula (1) formula (2) wherein: Z represents a radical of formula N(OH)CH( .dbd. O) or of formula C( .dbd. O)NH(OH); R1 represents hydrogen, methyl or trifluoromethyl, or, except when Z is a radical of | DE NOVO PHARMACEUTICALS LTD. (GB) | 2008-01-29 | — | — | US | disclosed |
| US-20040102491-A1 | Antimicrobial agents | DE NOVO PHARMACEUTICALS LTD. (GB) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102491-A1 | Antimicrobial agents | CBR1, CYC1, MRM1 | TGM2 2786/4885HTT 3820/4885LMNA 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.