Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 6/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3558592 | 0.83 | ALDH1A1 (0.59) | ALDH1A1POLBRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3555192 | 0.77 | ALDH1A1 (0.61) | ALDH1A1POLBRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL3554578 | 0.71 | HDAC1 (0.47) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL19087149 | 0.70 | HSD17B10 (0.70) | ALDH1A1POLBSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL3553873 | 0.69 | HDAC1 (0.63) | ALDH1A1RAB9ASMN1; SMN2L3MBTL1HTT | |
| SCHEMBL3556580 | 0.68 | HDAC1 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL3549681 | 0.68 | HDAC2 (0.59) | ALDH1A1POLBSMN1; SMN2LMNAMAPT | |
| SCHEMBL130830 | 0.67 | L3MBTL1 (0.62) | ALDH1A1POLBRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL17221323 | 0.67 | KLKB1 (0.56) | ALDH1A1RAB9AL3MBTL1GAALMNA | |
| SCHEMBL4516147 | 0.67 | LMNA (0.70) | ALDH1A1POLBRAB9ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904452-A2 | HISTONE DEACETYLASE INHIBITORS | Takeda San Diego, Inc. (US) | 2008-04-02 | — | — | EP | claimed |
| WO-2007011626-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2007-01-25 | — | — | WO | claimed |