Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15815775 | 0.94 | GABRA1 (0.49) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL10051848 | 0.88 | ESR1 (0.47) | ESR1ESR2PDK2MEN1KMT2A | |
| SCHEMBL15814218 | 0.86 | ESR1 (0.50) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL20233960 | 0.85 | DHFR (0.41) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL6949064 | 0.85 | ESR1 (0.51) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL7723158 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL219581 | 0.80 | ESR1 (0.55) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL30306994 | 0.80 | ESR1 (0.55) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL30853252 | 0.80 | ESR1 (0.55) | GABRA1GABRB2ESR1ESR2AKR1B1 | |
| SCHEMBL7719015 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2ESR1ESR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008273844-A | NEW FLUORENE COMPOUND HAVING PHENOLIC HYDROXY GROUP AND METHYLOL GROUP AND METHOD FOR PRODUCING THE SAME | OSAKA GAS CO LTD | 2008-11-13 | — | — | JP | disclosed |