SCHEMBL6742810

SCHEMBL6742810

O=C(O)Cl.O=C1CCC(=O)N1O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA9 Q16790 1/20 0.35
MAPK1 P28482 1/20 0.33
ALDH1A1 P00352 2/20 0.31
PKM P14618 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL6150295 0.88 CA1 (0.38) CA12CA1CA9MAPK1ALDH1A1
Bicarbonate SCHEMBL14917 0.88 CA1 (0.38) CA12CA1CA9MAPK1ALDH1A1
Oxalic Acid SCHEMBL9728851 0.86 CA12 (0.37) CA12CA1CA9MAPK1ALDH1A1
SCHEMBL338264 0.85 KDM4E (0.34) CA12CA1CA9ALDH1A1POLB
SCHEMBL1123 0.85
SCHEMBL785147 0.85
Carbamic Acid SCHEMBL699756 0.83 ACHE (0.39) CA12CA1CA9ALDH1A1PKM
Acetic Acid SCHEMBL21834859 0.83 FFAR3 (0.39) CA12CA1CA9ALDH1A1PKM
Acetic Acid SCHEMBL482738 0.83 FFAR3 (0.39) CA12CA1CA9ALDH1A1PKM
Chloroacetic Acid SCHEMBL23933668 0.82 TSHR (0.48) CA12CA1CA9ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120037406-A Step-by-step targeting placenta trophoblast micro-nano robot and preparation method and application thereof 重庆医科大学附属第一医院 2025-05-27 CN claimed
CN-111171174-B Glucan derivatives, process for their preparation and agents for their use in the preparation of medicaments 上海图珐医药科技有限公司 2022-02-01 CN claimed
CN-111171174-A Glucan derivatives, process for their preparation and agents for their use in the preparation of medicaments 上海图珐医药科技有限公司 2020-05-19 CN claimed
JP-62252800-A None JP disclosed
CN-120037406-A Step-by-step targeting placenta trophoblast micro-nano robot and preparation method and application thereof 重庆医科大学附属第一医院 2025-05-27 CN disclosed
CN-118922433-A Method for producing Fc molecule-containing modifying agent 日本医事物理股份有限公司 2024-11-08 CN disclosed
CN-118510548-A Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof 辉瑞公司 2024-08-16 CN disclosed
CN-116710138-A Peptide crosslinking agent and crosslinked peptide crosslinked by the same 国立大学法人鹿儿岛大学 2023-09-05 CN disclosed
CN-115813902-A Use of substituted hexitols for the treatment of malignant tumors 德玛公司 2023-03-21 CN disclosed
CN-115778934-A Use of substituted hexitols for the treatment of malignant tumors 德玛公司 2023-03-14 CN disclosed
CN-114401983-A Hemoglobin-based therapeutic agents 环喜有限公司 2022-04-26 CN disclosed
EP-0510393-B1 Biocompatible, low protein adsorption affinity matrix GRACE W R & CO (US) 1995-10-04 EP disclosed
US-5403750-A Polyetherurethanes modified with amine, mercpto or hydroxyl functional groups W. R. GRACE & CO.-CONN. (US) 1995-04-04 US disclosed
EP-0510393-A1 Biocompatible, low protein adsorption affinity matrix W.R. Grace & Co.-Conn. (US) 1992-10-28 EP disclosed
US-5053133-A Biochemical immobilization MEMBRANA GMBH (DE) 1991-10-01 US disclosed
EP-0441660-A1 Affinity separation with activated polyamide microporous membranes Klein, Elias (US) 1991-08-14 EP disclosed
US-4894468-A CHROMATOGRAPHY, SILANETRIOL MODIFIED SILICA YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1990-01-16 US disclosed
EP-0244802-A2 Substituted silica YEDA RESEARCH AND DEVELOPMENT COMPANY LIMITED (IL) 1987-11-11 EP disclosed
JP-S62252800-A PRODUCTION OF CHEMICALLY MODIFIED PROTEIN BITAMIN KENKYUSHO:KK 1987-11-04 JP disclosed
US-4341707-A CHEMICAL INTERMEDIATES; PEPTIDE SYNTHESIS Ogura, Haruo (JP) 1982-07-27 US disclosed