Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320181 | 0.78 | NPC1 (0.56) | RIPK1HDAC1HDAC6ALDH1A1TSHR | |
| SCHEMBL9550228 | 0.77 | NPC1 (0.50) | HDAC8HDAC1HDAC6HDAC3HDAC2 | |
| SCHEMBL11835115 | 0.76 | LMNA (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6378572 | 0.75 | GRIN2D (0.56) | ALOX5RIPK1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL11834236 | 0.73 | HDAC1 (0.54) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3279004 | 0.72 | ALOX5 (0.60) | ALOX5RIPK1ALDH1A1TSHRNPC1 | |
| SCHEMBL11127627 | 0.70 | MGLL (0.52) | ALOX5RIPK1ALDH1A1TSHRNPC1 | |
| SCHEMBL2462058 | 0.69 | TSHR (0.64) | ALDH1A1TSHRNPC1RAB9AMEN1 | |
| SCHEMBL11127626 | 0.68 | ALOX5 (0.56) | ALOX5RIPK1ALDH1A1TSHRNPC1 | |
| SCHEMBL13641355 | 0.68 | NPC1 (0.58) | RIPK1ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381542-B2 | Nucleic acids encoding a biogenic amine receptor | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-06-03 | — | — | US | disclosed |
| US-20040072187-A1 | Novel mammalian receptor genes and uses | OREGON HEALTH & SCIENCE UNIVERSITY | 2004-04-15 | — | — | US | disclosed |