Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4834066 | 0.99 | CCR2 (0.51) | CCR2TACR1KMT2AUSP2CYP3A4 | |
| SCHEMBL4838738 | 0.88 | KMT2A (0.49) | KMT2ASMN1; SMN2ALDH1A1MAPK1OPRM1 | |
| SCHEMBL4831071 | 0.87 | KMT2A (0.48) | TACR1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4831009 | 0.87 | KMT2A (0.48) | TACR1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4830947 | 0.87 | ALDH1A1 (0.55) | TACR1KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4836256 | 0.87 | KMT2A (0.48) | TACR1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4836884 | 0.86 | ALDH1A1 (0.54) | TACR1KMT2ASMN1; SMN2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL4827786 | 0.86 | KMT2A (0.47) | TACR1KMT2ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4836644 | 0.85 | TACR1 (0.49) | TACR1KMT2ACYP3A4SMN1; SMN2ALDH1A1 | |
| SCHEMBL4833925 | 0.85 | KMT2A (0.46) | KMT2AMEN1RAB9ANPC1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351713-B2 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | VIRO CHEM PHARMA, INC. (CA) | 2008-04-01 | — | — | US | claimed |
| US-20050075360-A1 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | VIRO CHEM PHARMA, INC. (CA) | 2005-04-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050075360-A1 | Spirohydantoin compounds and methods for the modulation of chemokine receptor activity | CXCR1, CXCR4, CXCR2 | CCR2 6/4885TACR1 39/4885KMT2A 4243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.