SCHEMBL482809

SCHEMBL482809

Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)=Cc2cc(S(=O)(=O)N(C)C)ccc2OC(C)C)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.35
FFAR4 Q5NUL3 1/20 0.32
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29555304 0.91 POLB (0.34) POLB
SCHEMBL12540503 0.86 MAPT (0.34) POLBLMNASMN1; SMN2
SCHEMBL29814403 0.83 POLB (0.35) POLBFFAR4KDM4ELMNASMN1; SMN2
SCHEMBL1194744 0.83 CYP19A1 (0.35) POLBLMNASMN1; SMN2HTT
SCHEMBL29380873 0.83 CYP19A1 (0.35) POLBLMNASMN1; SMN2HTT
SCHEMBL314391 0.83 POLB (0.32) POLBFFAR4KDM4ELMNASMN1; SMN2
SCHEMBL1244265 0.82 SMN1; SMN2 (0.33) LMNASMN1; SMN2HTT
SCHEMBL16390035 0.82 POLB (0.35) POLBFFAR4KDM4ELMNASMN1; SMN2
SCHEMBL16390037 0.81 POLB (0.35) POLBFFAR4KDM4ELMNASMN1; SMN2
Hydrochloric Acid SCHEMBL482808 0.81 POLB (0.36) POLBFFAR4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612352-B2 Process for preparing perfuming intermediate FIRMENICH SA (CH) 2026-04-28 US claimed
US-20240368068-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATES FIRMENICH SA (CH) 2024-11-07 US claimed
EP-4367109-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATES Firmenich SA (CH) 2024-05-15 EP claimed
US-20230095887-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE FIRMENICH SA (CH) 2023-03-30 US claimed
WO-2023036732-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATES FIRMENICH SA (CH) 2023-03-16 WO claimed
EP-4069667-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE Firmenich SA (CH) 2022-10-12 EP claimed
CN-115003649-A Process for the preparation of perfuming intermediates 弗门尼舍有限公司 2022-09-02 CN claimed
EP-3126407-B1 SPACER GROUPS FOR FUNCTIONALIZED RESINS IN TIRES EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-08-03 EP claimed
EP-3077433-B1 FUNCTIONALIZED RESINS FOR HIGH PERFORMANCE TIRES EXXONMOBIL CHEMICAL PATENTS INC (US) 2022-04-20 EP claimed
WO-2021176009-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE FIRMENICH SA (CH) 2021-09-10 WO claimed
US-20130281626-A1 Polyolefin Compositions and Methods of Production Thereof EXXONMOBIL CHEMICAL PATENTS INC. 2013-10-24 US claimed
US-20130137829-A1 Functionalization of Vinyl Terminated Polymers by Ring Opening Cross Metathesis EXXONMOBIL CHEMICAL PATENTS INC. 2013-05-30 US claimed
US-20130041122-A1 Polymers Prepared By Ring Opening / Cross Metathesis EXXONMOBIL CHEMICAL PATENTS INC. 2013-02-14 US claimed
US-8283419-B2 Olefin functionalization by metathesis reaction EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-09 US claimed
WO-2012134722-A2 DIBLOCK COPOLYMERS PREPARED BY CROSS METATHESIS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-04 WO claimed
US-20120245294-A1 Olefin Triblock Polymers via Ring-Opening Metathesis Polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2012-09-27 US claimed
JP-2011525213-A 2011-09-15 JP claimed
EP-2318446-A2 OLEFIN FUNCTIONALIZATION BY METATHESIS REACTION ExxonMobil Chemical Patents Inc. (US) 2011-05-11 EP claimed
US-20090318647-A1 Olefin Functionalization By Metathesis Reaction EXXONMOBIL CHEMICAL PATENTS INC. 2009-12-24 US claimed
WO-2009155517-A2 OLEFIN FUNCTIONALIZATION BY METATHESIS REACTION EXXONMOBIL CHEMICAL PATENT INC. (US) 2009-12-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12612352-B2 Process for preparing perfuming intermediate CBR1, CYP2E1, CBR3 POLB 466/4885FFAR4 1852/4885KDM4E 3983/4885
US-20240368068-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATES POR, PPOX, ACLY POLB 196/4885FFAR4 2093/4885KDM4E 4155/4885
US-20230095887-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATE POR, CYP1B1, CYP1A2 POLB 212/4885FFAR4 4012/4885KDM4E 4639/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.