Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3670820 | 0.85 | POLB (0.38) | POLBFFAR4HTTMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL2133160 | 0.84 | POLB (0.38) | POLBFFAR4HTTMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL14118040 | 0.84 | POLB (0.38) | POLBFFAR4HTTMAPTNPSR1 | |
| SCHEMBL29886623 | 0.83 | POLB (0.36) | POLBFFAR4HTTMAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL314389 | 0.82 | POLB (0.33) | POLBFFAR4HTR6MAPTNPSR1 | |
| SCHEMBL29814403 | 0.81 | POLB (0.35) | POLBFFAR4HTT | |
| SCHEMBL482809 | 0.81 | POLB (0.35) | POLBFFAR4HTT | |
| SCHEMBL16390037 | 0.81 | POLB (0.35) | POLBFFAR4HTT | |
| Hydrochloric Acid SCHEMBL3703679 | 0.79 | AR (0.33) | MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL14698638 | 0.77 | POLB (0.33) | POLBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12612352-B2 | Process for preparing perfuming intermediate | FIRMENICH SA (CH) | 2026-04-28 | — | — | US | claimed |
| US-20240368068-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATES | FIRMENICH SA (CH) | 2024-11-07 | — | — | US | claimed |
| EP-4367109-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATES | Firmenich SA (CH) | 2024-05-15 | — | — | EP | claimed |
| US-20230095887-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATE | FIRMENICH SA (CH) | 2023-03-30 | — | — | US | claimed |
| WO-2023036732-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATES | FIRMENICH SA (CH) | 2023-03-16 | — | — | WO | claimed |
| EP-3126407-B1 | SPACER GROUPS FOR FUNCTIONALIZED RESINS IN TIRES | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2022-08-03 | — | — | EP | claimed |
| EP-3077433-B1 | FUNCTIONALIZED RESINS FOR HIGH PERFORMANCE TIRES | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2022-04-20 | — | — | EP | claimed |
| WO-2021176009-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATE | FIRMENICH SA (CH) | 2021-09-10 | — | — | WO | claimed |
| US-9840569-B2 | Spacer groups for functionalized resins in tires | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-12-12 | — | — | US | claimed |
| EP-2897992-B1 | FUNCTIONALIZED RESINS OBTAINED VIA OLEFIN METATHESIS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2017-11-08 | — | — | EP | claimed |
| US-8669330-B2 | Olefin triblock polymers via ring-opening metathesis polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-03-11 | — | — | US | claimed |
| EP-2688921-A2 | DIBLOCK COPOLYMERS PREPARED BY CROSS METATHESIS | Exxonmobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | claimed |
| US-20130281626-A1 | Polyolefin Compositions and Methods of Production Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2013-10-24 | — | — | US | claimed |
| US-20130041122-A1 | Polymers Prepared By Ring Opening / Cross Metathesis | EXXONMOBIL CHEMICAL PATENTS INC. | 2013-02-14 | — | — | US | claimed |
| US-8283419-B2 | Olefin functionalization by metathesis reaction | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-09 | — | — | US | claimed |
| WO-2012134722-A2 | DIBLOCK COPOLYMERS PREPARED BY CROSS METATHESIS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | claimed |
| JP-2011525213-A | — | — | 2011-09-15 | — | — | JP | claimed |
| EP-2318446-A2 | OLEFIN FUNCTIONALIZATION BY METATHESIS REACTION | ExxonMobil Chemical Patents Inc. (US) | 2011-05-11 | — | — | EP | claimed |
| US-20090318647-A1 | Olefin Functionalization By Metathesis Reaction | EXXONMOBIL CHEMICAL PATENTS INC. | 2009-12-24 | — | — | US | claimed |
| WO-2009155517-A2 | OLEFIN FUNCTIONALIZATION BY METATHESIS REACTION | EXXONMOBIL CHEMICAL PATENT INC. (US) | 2009-12-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12612352-B2 | Process for preparing perfuming intermediate | CBR1, CYP2E1, CBR3 | POLB 466/4885FFAR4 1852/4885HTT 4803/4885 |
| US-20240368068-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATES | POR, PPOX, ACLY | POLB 196/4885FFAR4 2093/4885HTT 4771/4885 |
| US-20230095887-A1 | PROCESS FOR PREPARING PERFUMING INTERMEDIATE | POR, CYP1B1, CYP1A2 | POLB 212/4885FFAR4 4012/4885HTT 4538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.