SCHEMBL4828375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26728280	0.81	ATM (0.71)	NPC1RAB9AATMALDH1A1HPGD
	SCHEMBL2540650	0.81	ATM (0.61)	NPC1RAB9AATMMAPTALDH1A1
	SCHEMBL1092875	0.80	ATM (1.00)	NPC1RAB9AATMALDH1A1HPGD
	SCHEMBL653025	0.80	PKM (0.87)	ATMALDH1A1HPGDTSHRPKM
	SCHEMBL4831672	0.78	ATM (0.72)	NPC1RAB9AATMMAPTALDH1A1
	SCHEMBL1535157	0.78	ATM (0.72)	NPC1RAB9AATMMAPTALDH1A1
	SCHEMBL13516975	0.78	MEN1 (0.83)	NPC1RAB9AATMALDH1A1HPGD
	SCHEMBL102971	0.78	KDM4E (0.89)	NPC1RAB9AATMMAPTHPGD
	SCHEMBL2394331	0.78	NPC1 (0.69)	NPC1RAB9AATMMAPTALDH1A1
	SCHEMBL13516438	0.78	ALDH1A1 (0.76)	NPC1RAB9AATMMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.