Benzimidazole

Benzimidazole

SCHEMBL4829679

O=C(O)c1cc2cccc3c4c(C(=O)O)ccc5c(C(=O)O)c(C(=O)O)cc(c(c1)c23)c54.c1ccc2[nH]cnc2c1.c1ccc2[nH]cnc2c1

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 2/20 0.36
WNT3A P56704 2/20 0.36
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.35
PDE10A Q9Y233 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
PTPN1 P18031 1/20 0.34
MGAM O43451 1/20 0.34
NPC1 O15118 1/20 0.34
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.32
MAP2K4 P45985 1/20 0.32
MAPKAPK3 Q16644 1/20 0.32
MAPK6 Q16659 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570619 0.85 KMT2A (0.46) KDM4EALDH1A1HPGDMEN1KMT2A
Benzimidazole SCHEMBL1199356 0.81 KMT2A (0.39) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL442159 0.79 PDE10A (0.38) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL2695888 0.79 PDE10A (0.38) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL27651909 0.78 PDE10A (0.38) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL10625309 0.75 RAB9A (0.44) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL36282 0.75 RAB9A (0.44) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL2496637 0.73 RAB9A (0.49) CTNNB1WNT3AKDM4EALDH1A1HPGD
Benzimidazole SCHEMBL30988876 0.73 KMT2A (0.44) CTNNB1WNT3AKDM4EALDH1A1HPGD
Naphthoic Acid SCHEMBL4756576 0.72 NR4A1 (0.60) KDM4EALDH1A1HPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291223-B2 Epitaxial organic layered structure and method for making NITTO DENKO CORPORATION (JP) 2007-11-06 US claimed
JP-2007504305-A 2007-03-01 JP claimed
US-7166161-B2 Anisotropic film manufacturing NITTO DENKO CORPORATION (JP) 2007-01-23 US claimed
CN-1846461-A Epitaxial organic layered structure and method for making NITTO DENKO CORP (JP) 2006-10-11 CN claimed
US-20050103258-A1 Epitaxial organic layered structure and method for making INSOLVENCY SERVICES GROUP, INC. 2005-05-19 US claimed
WO-2005032217-A1 EPITAXIAL ORGANIC LAYERED STRUCTURE AND METHOD FOR MAKING NITTO DENKO CORPORATION (JP) 2005-04-07 WO claimed
WO-2004065524-A1 ANISOTROPIC FILM MANUFACTURING NITTO DENKO CORPORATION (JP) 2004-08-05 WO claimed
US-20040142183-A1 Anisotropic film manufacturing INSOLVENCY SERVICES GROUP, INC. 2004-07-22 US claimed
US-7411715-B2 Electrooptical devices, electrooptical thin crystal films and methods making same NITTO DENKO CORPORATION (JP) 2008-08-12 US disclosed
CN-100378491-C Interferential optical filter NITTO ELECTRIC IND CO (JP) 2008-04-02 CN disclosed
US-7291223-B2 Epitaxial organic layered structure and method for making NITTO DENKO CORPORATION (JP) 2007-11-06 US disclosed
US-7190416-B2 Liquid crystal display with touch panel having internal front polarizer NITTO DENKO CORPORATION (JP) 2007-03-13 US disclosed
US-7166161-B2 Anisotropic film manufacturing NITTO DENKO CORPORATION (JP) 2007-01-23 US disclosed
CN-1846461-A Epitaxial organic layered structure and method for making NITTO DENKO CORP (JP) 2006-10-11 CN disclosed
WO-2004065524-A1 ANISOTROPIC FILM MANUFACTURING NITTO DENKO CORPORATION (JP) 2004-08-05 WO disclosed
US-20040142183-A1 Anisotropic film manufacturing INSOLVENCY SERVICES GROUP, INC. 2004-07-22 US disclosed
WO-2004036293-A2 LIQUID CRYSTAL DISPLAY WITH TOUCH PANEL OPTIVA, INC. (US) 2004-04-29 WO disclosed
US-20040075779-A1 Liquid crystal display with touch panel INSOLVENCY SERVICES GROUP, INC. 2004-04-22 US disclosed
US-20030161022-A1 Electrooptical devices, electrooptical thin crystal films and methods making same OPTIVA, INC. 2003-08-28 US disclosed
WO-2003044591-A1 ELECTROOPTICAL DEVICES, ELECTROOPTICAL THIN CRYSTAL FILMS AND METHODS MAKING SAME OPTIVA, INC. (US) 2003-05-30 WO disclosed