SCHEMBL48303

SCHEMBL48303

O=C=Nc1cc2cc3cc4ccccc4cc3cc2cc1N=C=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.45
TRPA1 O75762 1/20 0.39
ALDH1A1 P00352 5/20 0.38
TDP1 Q9NUW8 4/20 0.38
HSD17B10 Q99714 3/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
HIF1A Q16665 2/20 0.38
ALOX15 P16050 2/20 0.38
HBB P68871 1/20 0.38
HPGD P15428 4/20 0.37
MAPT P10636 2/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
RAD52 P43351 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
MAPK1 P28482 2/20 0.33
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
GABRA1 P14867 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL661077 0.95 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL29589760 0.95 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL1169526 0.80 CYP3A4 (0.43) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL3714186 0.79 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL3714131 0.78 TDP1 (0.48) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL3904604 0.77 ALDH1A1 (0.55) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL48435 0.75 ALDH1A1 (0.36) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL15431 0.75 CYP3A4 (0.64) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL29395383 0.75 CYP3A4 (0.64) CYP3A4TRPA1ALDH1A1TDP1HSD17B10
SCHEMBL11334193 0.74 CYP3A4 (0.48) CYP3A4TRPA1ALDH1A1TDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 959 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247676-B2 For golf balls with non-ionomer casing layer ACUSHNET COMPANY (US) 2007-07-24 US claimed
US-7041743-B2 Thin-layer-covered golf ball with improved velocity ACUSHNET COMPANY (US) 2006-05-09 US claimed
US-6949595-B2 Multi-layer golf ball with translucent cover ACUSHNET COMPANY (US) 2005-09-27 US claimed
US-6939907-B2 Golf balls comprising highly-neutralized acid polymers ACUSHNET COMPANY (US) 2005-09-06 US claimed
US-20050148409-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2005-07-07 US claimed
US-6894098-B2 Golf balls comprising highly-neutralized acid polymers ACUSHNET COMPANY (US) 2005-05-17 US claimed
US-20050085590-A1 multilayer; interior covering blend of styrene copolymer and polyisoprene; exterior covering of polyurethanes, polyureas JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-04-21 US claimed
US-20040176531-A1 Multi-layer golf ball with translucent cover JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-09-09 US claimed
US-20040176185-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US claimed
US-20040176184-A1 Multi-layer golf ball with translucent cover ACUSHNET COMPANY 2004-09-09 US claimed
US-20040092667-A1 Thin-layer-covered golf ball with improved velocity JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-05-13 US claimed
US-20040082406-A1 Reaction injection moldable compositions, methods for making same, and resultant golf articles JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-04-29 US claimed
US-6645088-B2 Reaction injection moldable compositions, methods for making same, and resultant golf articles ACUSHNET COMPANY 2003-11-11 US claimed
US-20030158352-A1 Golf balls comprising highly-neutralized acid polymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-08-21 US claimed
US-20030144087-A1 Golf balls comprising highly-neutralized acid polymers JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2003-07-31 US claimed
US-20020173379-A1 Reaction injection moldable compositions, methods for making same, and resultant golf articles JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2002-11-21 US claimed
US-20020086743-A1 Urethane elastomers with improved color stability ACUSHNET COMPANY 2002-07-04 US claimed
EP-4479455-B1 ASPARTIC ACID ESTER-FUNCTIONAL POLYSILOXANES, THEIR PREPARATION AND USE THEREOF MOMENTIVE PERFORMANCE MAT GMBH (DE) 2026-04-01 EP disclosed
US-20020006837-A1 Wound golf ball having cast polyurethane cover ACUSHNET COMPANY 2002-01-17 US disclosed
US-20010024982-A1 Thin-layer-covered multilayer golf ball JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2001-09-27 US disclosed