Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9229488 | 0.94 | CYP3A4 (0.54) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL1169526 | 0.86 | CYP3A4 (0.43) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL6858063 | 0.82 | CYP1A2 (0.43) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| Alpha-Naphthylisocyanate SCHEMBL29400034 | 0.82 | CYP1A2 (0.64) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| Alpha-Naphthylisocyanate SCHEMBL374 | 0.82 | CYP1A2 (0.64) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL3166446 | 0.81 | ALDH1A1 (0.69) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL48435 | 0.80 | ALDH1A1 (0.36) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| Alpha-Naphthylisocyanate SCHEMBL3333508 | 0.80 | CYP1A2 (0.62) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL48303 | 0.79 | CYP3A4 (0.45) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD | |
| SCHEMBL661077 | 0.79 | CYP3A4 (0.48) | CYP3A4ALDH1A1CYP1A2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | claimed |
| US-10800747-B2 | Macrocyclic compounds | ZIYLO LTD (GB) | 2020-10-13 | — | — | US | disclosed |
| US-9760006-B2 | Silicon-containing resist underlayer film forming composition having urea group | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-09-12 | — | — | US | disclosed |
| CN-101910949-B | Composition for forming resist underlayer film containing silicon and having urea group | NISSAN CHEMICAL IND LTD | 2013-07-24 | — | — | CN | disclosed |
| CN-101910949-A | Composition for forming resist underlayer film containing silicon and having urea group | NISSAN CHEMICAL IND LTD | 2010-12-08 | — | — | CN | disclosed |
| US-20100291487-A1 | SILICON-CONTAINING RESIST UNDERLAYER FILM FORMING COMPOSITION HAVING UREA GROUP | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2010-11-18 | — | — | US | disclosed |
| WO-2010112946-A1 | ADAMANTANE BISUREA DERIVATIVES, METHOD OF PREPARATION AND APPLICATION IN ANION SENSING | RUDJER BOSKOVIC INSTITUTE (HR) | 2010-10-07 | — | — | WO | disclosed |
| US-20100152434-A1 | Protein Kinase-binding Nucleosides and Associated Methods | BRIGHAM YOUNG UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-20100152434-A1 | Protein Kinase-binding Nucleosides and Associated Methods | BRIGHAM YOUNG UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| WO-2008151024-A1 | PROTEIN KINASE-BINDING NUCLEOSIDES AND ASSOCIATED METHODS | BRIGHAM YOUNG UNIVERSITY (US) | 2008-12-11 | — | — | WO | disclosed |
| EP-0062611-B1 | PHOTOPOLYMERISATION PROCESS | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4413052-A | Photopolymerization process employing compounds containing acryloyl group and anthryl group | CIBA-GEIGY CORPORATION (US) | 1983-11-01 | — | — | US | disclosed |
| EP-0062611-A2 | Photopolymerisation process | CIBA-GEIGY AG (CH) | 1982-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800747-B2 | Macrocyclic compounds | SLC2A4, GALE, MPI | CYP3A4 605/4885ALDH1A1 2107/4885CYP1A2 2645/4885 |
| US-20100152434-A1 | Protein Kinase-binding Nucleosides and Associated Methods | ADK, DCK, NME2 | CYP3A4 4777/4885ALDH1A1 4265/4885CYP1A2 4852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.