SCHEMBL48311

SCHEMBL48311

CCSC(C)n1cncc2ncnc1-2

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48370 0.68 LTA4H (0.46) LTA4HADORA2AADORA1
SCHEMBL48312 0.67 LTA4H (0.45) LTA4H
SCHEMBL11109615 0.64 CYP3A4 (0.31)
SCHEMBL1535169 0.62 LTA4H (0.36) LTA4H
SCHEMBL6639614 0.62 LTA4H (0.36) LTA4H
SCHEMBL28137790 0.62 LTA4H (0.36) LTA4H
SCHEMBL276781 0.62 LTA4H (0.36) LTA4H
SCHEMBL276782 0.62 LTA4H (0.36) LTA4H
SCHEMBL18507240 0.59 CYP19A1 (0.36)
SCHEMBL5675147 0.58 LTA4H (0.43) LTA4HADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2028272-B1 METHOD OF MODIFYING NUCLEOTIDE CHAIN PANASONIC CORP (JP) 2014-01-08 EP disclosed
EP-1647592-B1 METHOD OF MODIFYING NUCLEOTIDE CHAIN PANASONIC CORP (JP) 2009-03-11 EP disclosed
EP-2028272-A1 METHOD OF MODIFYING NUCLEOTIDE CHAIN Panasonic Corporation (JP) 2009-02-25 EP disclosed
EP-1647592-A1 METHOD OF MODIFYING NUCLEOTIDE CHAIN MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-04-19 EP disclosed