Quinoline

Quinoline

SCHEMBL4831356

[H+].c1ccc2ncccc2c1

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.94
NPC1 O15118 2/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
CYP3A4 P08684 3/20 0.54
MAPT P10636 4/20 0.52
HTT P42858 3/20 0.52
KDM4E B2RXH2 3/20 0.52
CASP1 P29466 2/20 0.52
TP53 P04637 2/20 0.52
HSP90AA1 P07900 2/20 0.52
TSHR P16473 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 1/20 0.52
CASP7 P55210 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C19 P33261 1/20 0.52
NR4A2 P43354 1/20 0.52
HSP90AB1 P08238 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL28008945 1.00 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27547943 1.00 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL27544818 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28224950 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28024965 0.97 ALDH1A1 (0.90) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29349552 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL1270969 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL32661377 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29822171 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL2774 0.97 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110358192-A Potent anti-aging wear-resisting brush filament of one kind and preparation method thereof 安徽省恒昌刷业有限公司 2019-10-22 CN claimed
CN-110294770-A A kind of cephalosporanic olefinic salt compound, preparation method and in the method for the compound synthesis Cefquinome 齐鲁晟华制药有限公司 2019-10-01 CN claimed
CN-110152654-A Ordered mesopore carbon-TiO2Composite material loaded palladium catalyst and preparation method thereof, application 上海师范大学 2019-08-23 CN claimed
CN-110117282-A A kind of zinc ion fluorescent compound and the preparation method and application thereof 五邑大学 2019-08-13 CN claimed
CN-109851953-A A kind of towline control cable and preparation method thereof 宝胜科技创新股份有限公司 2019-06-07 CN claimed
CN-109206454-A One kind is based on the tetra- serobila selective probe of G- of double-core iridium (III) complex 青岛农业大学 2019-01-15 CN claimed
CN-109096738-A A kind of novel tree epoxy-type artificial stone and preparation method thereof 宁波蒙曼生物科技有限公司 2018-12-28 CN claimed
CN-109053725-A A kind of 2- (tetrahydroquinoline -6- base)-tetrahydro -1,8- naphthyridine type compound and the preparation method and application thereof 五邑大学 2018-12-21 CN claimed
CN-108727262-A A kind of synthetic method of the bromo- 7- methoxy quinolines of 3- 苏州康润医药有限公司 2018-11-02 CN claimed
CN-108544136-A A kind of high activity rosin flux 苏州锐耐洁电子科技新材料有限公司 2018-09-18 CN claimed
CN-101585808-A Method for asymmetric catalytic hydrogenation of quinoline derivatives CHINESE ACAD INST CHEMISTRY (CN) 2009-11-25 CN claimed
CN-101212971-A 4-phenyl-5-0x0-l,4,5,6,7,8-hexahydr0quin0line derivatives as medicaments for the treatment of infertility ORGANON NV (NL) 2008-07-02 CN claimed
CN-101212972-A 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility ORGANON NV (NL) 2008-07-02 CN claimed
CN-101212973-A 4-phenyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives as medicaments for the treatment of infertility ORGANON NV (NL) 2008-07-02 CN claimed
CN-1681470-A Agent for dyeing keratinous fibres HENKEL KGAA (DE) 2005-10-12 CN claimed
CN-1174042-C Method of making washable, dryable elastic erticles �Ϻ���ͨ��ѧ 2004-11-03 CN claimed
CN-1158258-C Alpha 1 beta-adrenergic receptor antagonists ������������ʽ���� 2004-07-21 CN claimed
CN-1327444-A Alpha 1 beta-adrenergic receptor antagonists TORAY INDUSTRIES (JP) 2001-12-19 CN claimed
CN-1304436-A Process for making washable, dryable elastomeric articles DOW CHEMICAL CO (US) 2001-07-18 CN claimed
CN-87103560-A Pharmaceutical composition 1988-05-18 CN claimed