Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10628700 | 0.98 | EGFR (0.45) | EGFRKCNH2BCHEACHELMNA | |
| SCHEMBL10628492 | 0.98 | EGFR (0.45) | EGFRKCNH2BCHEACHELMNA | |
| SCHEMBL303152 | 0.98 | EGFR (0.45) | EGFRKCNH2BCHEACHELMNA | |
| SCHEMBL10623988 | 0.98 | EGFR (0.45) | EGFRKCNH2BCHEACHELMNA | |
| SCHEMBL4267199 | 0.94 | BCHE (0.42) | EGFRKCNH2BCHEACHELMNA | |
| SCHEMBL13900817 | 0.91 | EGFR (0.40) | EGFRKCNH2BCHEACHETDP1 | |
| SCHEMBL10626718 | 0.86 | NPC1 (0.42) | BCHEACHENPC1L3MBTL1RELA | |
| SCHEMBL28888672 | 0.80 | NPC1 (0.43) | EGFRKCNH2BCHEACHETDP1 | |
| (Z)-1,2-Diphenylethene SCHEMBL28882092 | 0.80 | RELA (0.54) | EGFRLMNAHDAC3TDP1TP53 | |
| SCHEMBL136178 | 0.78 | NPC1 (0.48) | TDP1NPC1L3MBTL1RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | claimed |
| WO-2008058939-A2 | UV-SENSITIVE ELEMENTS WITH TRIARYLAMINE DERIVATIVES AS SENSITIZERS FOR CTP EXPOSURE | EASTMAN KODAK COMPANY (US) | 2008-05-22 | — | — | WO | disclosed |
| EP-1921500-A1 | UV-sensitive elements with triarylamine derivatives as sensitizers | EASTMAN KODAK COMPANY (US) | 2008-05-14 | — | — | EP | disclosed |
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-7276627-B2 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| US-6800410-B2 | PHOTOCONDUCTOR, CHARGER, IRRADIATOR; FORMING ELECTROSTATICS LATENT IMAGES; OPTICAL WRITING USING LASERS | RICOH COMPANY, LTD. (JP) | 2004-10-05 | — | — | US | disclosed |
| US-20030218665-A1 | Image forming apparatus | RICOH COMPANY, LTD. (JP) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060224017-A1 | One pot sequential reactions and novel products produced thereby | PNMT, CYP1A1, TERT | EGFR 4305/4885KCNH2 1162/4885BCHE 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.