Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.69 |
| ▸ | XDH | P47989 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 6/20 | 0.57 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5241998 | 0.90 | MAPT (0.74) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL7054594 | 0.90 | KDM4E (0.83) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL1675988 | 0.85 | RAB9A (0.71) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL29482681 | 0.84 | RAB9A (1.00) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL571161 | 0.84 | RAB9A (1.00) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL17718217 | 0.83 | KDM4E (0.76) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL2971118 | 0.82 | XDH (0.76) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL762092 | 0.82 | MAPT (1.00) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| 2'-Methoxyformonetin SCHEMBL234355 | 0.82 | KDM4E (1.00) | RAB9AMAPTNPC1KDM4EALDH1A1 | |
| 2'-Methoxyformonetin SCHEMBL29777010 | 0.82 | KDM4E (1.00) | RAB9AMAPTNPC1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323621-B2 | Method of decreasing liquiritigenin-derived isoflavones relative to total isoflavones in plants and plants producing reduced ratio of liquiritigenin-derived isoflavones relative to total isoflavones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-01-29 | — | — | US | disclosed |
| US-20040128714-A1 | Method of decreasing liquiritigenin-derived isoflavones relative to total isoflavones in plants and plants producing reduced ratio of liquiritigenin-derived isoflavones relative to total isoflavones | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-07-01 | — | — | US | disclosed |