SCHEMBL483233

SCHEMBL483233

NC1CCc2ccccc2N1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.48
PLAU P00749 1/20 0.45
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MTNR1A P48039 3/20 0.42
ANPEP P15144 4/20 0.40
NPC1 O15118 1/20 0.39
MAPK13 O15264 1/20 0.39
MAPK12 P53778 1/20 0.39
MAPK11 Q15759 1/20 0.39
MAPK14 Q16539 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1905381 0.98 SMYD3 (0.47) SMYD3PLAUGAAMAPTKDM4E
SCHEMBL5420694 0.88 MAPT (0.43) SMYD3PLAUGAAMAPTKDM4E
SCHEMBL1437747 0.79 PLAU (0.37) SMYD3PLAUGAAMEN1KMT2A
SCHEMBL5832175 0.78 GAA (0.50) SMYD3PLAUGAAMAPT
SCHEMBL19774297 0.78 MTNR1A (0.47) SMYD3PLAUGAAMAPTKDM4E
SCHEMBL20344534 0.77 ANPEP (0.50) SMYD3PLAUGAAMAPTMTNR1A
SCHEMBL4130897 0.75 MTNR1A (0.45) SMYD3GAAMAPTMTNR1ANPC1
SCHEMBL2697405 0.75 MTNR1A (0.45) SMYD3PLAUGAAMAPTKDM4E
SCHEMBL8771344 0.75 MTNR1A (0.42) SMYD3PLAUGAAMAPTKDM4E
SCHEMBL13305784 0.75 MTNR1A (0.45) SMYD3PLAUGAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039343-B Tetrahydroquinoline-amido metal catalyst, preparation method and application thereof 淄博鲁华泓锦新材料集团股份有限公司 2025-01-07 CN claimed
CN-119039343-A Tetrahydroquinoline-amido metal catalyst, preparation method and application thereof 淄博鲁华泓锦新材料集团股份有限公司 2024-11-29 CN claimed
EP-3694485-A1 SPECIFIC 7-AMINO-1,2,3,4-TETRAHYDROQUINOLINES, METHOD, AND COMPOSITION L'OREAL (FR) 2020-08-19 EP claimed
US-20150141877-A1 LED AND SHOCKWAVE THERAPY FOR TATTOO REMOVAL INREXREM INC. (US) 2015-05-21 US claimed
US-20140276246-A1 SYSTEM AND METHOD FOR TATTOO REMOVAL InrexRem 2014-09-18 US claimed
EP-1651190-B1 FORMULATIONS CONTAINING AN IMMUNE RESPONSE MODIFIER 3M INNOVATIVE PROPERTIES CO (US) 2012-09-19 EP claimed
EP-1784185-A4 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORP (US) 2009-06-03 EP claimed
US-7375180-B2 Methods and compositions related to IRM compounds and Toll-like receptor 8 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-20 US claimed
EP-1784185-A2 CHEMICAL COMPOUNDS SmithKline Beecham Corporation (US) 2007-05-16 EP claimed
EP-1592302-A4 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M INNOVATIVE PROPERTIES CO (US) 2007-04-25 EP claimed
WO-2006130399-A2 THERAPEUTIC COMBINATIONS AND METHODS INCLUDING IRM COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2006-12-07 WO claimed
WO-2006028896-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2006-03-16 WO claimed
EP-1603476-A2 METHOD OF TATTOO REMOVAL 3M Innovative Properties Company (US) 2005-12-14 EP claimed
EP-1592302-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M Innovative Properties Company (US) 2005-11-09 EP claimed
US-20050226878-A1 Therapeutic combinations and methods including IRM compounds 3M INNOVATIVE PROPERTIES COMPANY 2005-10-13 US claimed
CN-1610550-A Pharmaceutical formulations comprising an immune response modifier 3M INNOVATIVE PROPERTIES CO (US) 2005-04-27 CN claimed
WO-2004080292-A2 METHOD OF TATTOO REMOVAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-09-23 WO claimed
US-20040181211-A1 Method of tattoo removal 3M INNOVATIVE PROPERTIES COMPANY 2004-09-16 US claimed
WO-2004071459-A2 METHODS AND COMPOSITIONS RELATED TO IRM COMPOUNDS AND TOLL-LIKE RECEPTOR 8 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-08-26 WO claimed
US-20040162309-A1 Methods and compositions related to IRM compounds and toll-like receptor 8 3M INNOVATIVE PROPERTIES COMPANY 2004-08-19 US claimed